TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

EPIDERMICO [4 records]

Record 1 2021-12-20

English

Subject field(s)
  • Biotechnology
  • Immunology
  • Molecular Biology
CONT

CDR grafting has three fundamental components: (1) delimitation of CDRs [complementarity-determining regions] as regions determining the specificity of the nonhuman antibody and hence target for grafting, (2) selection of human FRs [framework regions] to be combined with nonhuman CDRs, and (3) assessment of conflicts between nonhuman CDRs and human FRs and design of back mutations to prevent a loss of affinity in the final product.

OBS

CDR grafting is the most frequently used rational design strategy for antibody humanization ...

French

Domaine(s)
  • Biotechnologie
  • Immunologie
  • Biologie moléculaire

Spanish

Campo(s) temático(s)
  • Biotecnología
  • Inmunología
  • Biología molecular
CONT

El Nimotuzumab, o h-R3, es un anticuerpo humanizado contra el receptor del factor de crecimiento epidérmico(EGF-R), generado mediante el trasplante de las regiones determinantes de la complementariedad o regiones hipervariables del anticuerpo murinoioregf/r3, en un marco de soporte de una inmunoglobulina humana.

Save record 1

Record 2 2014-09-29

English

Subject field(s)
  • Cytology
CONT

The protein called EGF-R sets off the chain reaction that activates the mucous gene. It binds with two molecules: transforming growth factor alpha and epidermal growth factor, which occur when tissues are inflamed by cigarette smoke, or some viruses and bacteria.

French

Domaine(s)
  • Cytologie
CONT

[...] anticorps monoclonaux qui ciblent le récepteur du facteur de croissance épidermique (R-EGF) présent à la surface d’une cellule cancéreuse. Le R-EGF envoie des signaux qui favorisent la croissance et la survie des cellules cancéreuses.

Spanish

Campo(s) temático(s)
  • Citología
CONT

Muchas células cancerosas tienen una proteína, conocida como receptor del factor de crecimiento epidérmico(EFGR), en su superficie, mientras que las células sanas no expresan esta proteína tan fuertemente. Conjugando, o uniendo las nanopartículas de oro a un anticuerpo contra el EFGR, llamado anti-EFGR, los investigadores pueden lograr que se unan a las células cancerígenas.

OBS

EFGR por sus siglas en inglés.

OBS

Ficha realizada en colaboración con los estudiantes del Certificado en Traducción español-inglés del Glendon College, York University, Toronto, Canada.

Save record 2

Record 3 2010-12-16

English

Subject field(s)
  • Epidermis and Dermis
OBS

The terms "epidermal," and "epidermic" are mostly used in technical texts.

French

Domaine(s)
  • Épiderme et derme
DEF

Relatif à l'épiderme ou qui en provient.

Spanish

Campo(s) temático(s)
  • Epidermis y dermis
Save record 3

Record 4 2002-03-21

English

Subject field(s)
  • Cytology
  • Biotechnology
DEF

A protein extractable from the submaxillary glands of male mice that stimulates proliferation of cells of ectodermal and mesodexmal origin and inhibits gastric secretion ....

French

Domaine(s)
  • Cytologie
  • Biotechnologie
CONT

[...] il est apparu que le récepteur du PDGF faisait partie d'une famille de récepteurs comprenant, entre autres, les récepteurs de l'insuline, de l'EGF (epidermal growth factor) et du CSF.I.

Spanish

Campo(s) temático(s)
  • Citología
  • Biotecnología
Save record 4

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