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IFN [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2024-11-26

English

Subject field(s)
  • Biological Sciences
  • Immunology
CONT

Interferons (IFNs) are cytokines produced and secreted by virtually all eukaryotic cells in response to stimulation by certain viruses, bacteria, antigens, and mitogens. They mediate their biological activity by binding to specific receptors on the cell surface. These proteins were named IFNs because they interfere with the viruses' replication ...

French

Domaine(s)
  • Sciences biologiques
  • Immunologie
CONT

Lorsque des cellules sont infectées par un virus, elles produisent des interférons (IFN), de puissantes molécules antivirales qui protègent les cellules avoisinantes de l'infection et permettent ainsi de limiter la propagation du virus dans l'organisme.

Spanish

Campo(s) temático(s)
  • Ciencias biológicas
  • Inmunología
DEF

Familia de proteínas naturales, entre 20 ó 15, producidas localmente por células específicas del organismo cuando hay un ataque por infecciones virales y que permiten que una célula se convierta en resistente a una amplia variedad de virus; constituyen una defensa temprana e inespecífica contra dichas infecciones.

OBS

Hay tres clases de interferones: alfa, beta y gamma.

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Record 2 2006-11-22

English

Subject field(s)
  • Cytology
  • Immunology
DEF

An "early warning" system that cells use to initiate an immune response against a viral infection.

OBS

A collective term for the acid-stable interferons IFN-alpha and IFN-beta which differ immunologically and with regard to some biologic and physiochemical properties. IFN-delta and IFN-kappa are also grouped as a Type-1 interferon.

French

Domaine(s)
  • Cytologie
  • Immunologie
DEF

Système d'alerte précoce que les cellules utilisent pour déclencher une réaction immunitaire contre un virus.

Spanish

Campo(s) temático(s)
  • Citología
  • Inmunología
DEF

Glicoproteína del grupo de las citocinas antivirales de clase 1 (interferones alfa y beta) que está involucrada en la respuesta inmune innata.

CONT

En el ser humano se han identificado tres tipos de interferones principales: alfa, beta y gamma. Los interferones alfa y beta integran la clase I y el interferón gamma la tipo II. Los interferones tipo I aumentan la función supresora inespecífica de las células T.

CONT

Las citocinas antivirales por excelencia son los interferones tipo I. Inhiben la replicación viral debido a que inducen en las células la síntesis de enzimas, tales como 2’-5’ oligoadenilato sintetasa, que colectivamente interfieren la replicación del ARN y ADN viral.

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