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VPU [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2011-11-02

English

Subject field(s)
  • Genetics
  • Biochemistry
  • Microbiology and Parasitology
DEF

A gene of HIV that influences viral replication.

OBS

Three HIV regulatory genes--tat, rev, and nef--and three so-called auxiliary genes--vif, vpr, and vpu--contain information necessary for the production of proteins that control the virus's ability to infect a cell, produce new copies of the virus or cause disease.

OBS

The vif (sor) and nef (3'orf) genes respectively encode and effect virus replication by increasing (vif) or decreasing (nef) virus production.

OBS

nef: negative factor.

Key term(s)
  • negative regulatory factor gene
  • negative regulatory factor
  • 3'orf

French

Domaine(s)
  • Génétique
  • Biochimie
  • Microbiologie et parasitologie
OBS

Le VIH-1 présente des gènes régulateurs. L'un d'eux, le gène F, aussi appelé 3'orf (pour open reading frame) et actuellement nef de l'anglais negative regulatory factor ou facteur de régulation négative est situé entre le gène env et la LTR [Long Terminal Repeat] de droite.

Key term(s)
  • facteur de régulation négative

Spanish

Campo(s) temático(s)
  • Genética
  • Bioquímica
  • Microbiología y parasitología
DEF

Gen que parece ser parte del sistema regulatorio del VIH, que lo hace ser más agresivo.

OBS

Los otros genes regulatorios del virus son el tat y el rev. Además existen otros tres genes virales auxiliares(vif, vpr, vpu) que contienen información pora la producción de proteínas que controlan la habilidad del VIH para infectar una célula, replicarse o causar enfermedad.

Save record 1

Record 2 2005-07-04

English

Subject field(s)
  • Biotechnology
  • Genetics
DEF

A 96-amino acid (14 kd) protein, which is incorporated into the virion. It interacts with the p6gag part of the Pr55gag precursor. Vpr detected in the cell is localized to the nucleus. Proposed functions for Vpr include the nuclear import of preintegration complexes, cell growth arrest,transactivation of cellular genes, and induction of cellular differentiation. Found in HIV-1, HIV-2, SIVmac and SIVmnd. It is homologous to VPX of SIVagm.

OBS

Glossary in molecular biology (Portions of the glossary text were taken directly or modified from definitions in the U.S. Congress Office of Technology Assessment document).

French

Domaine(s)
  • Biotechnologie
  • Génétique
DEF

Une des protéines du rétrovirus HIV-1 qui participe avec la protéine Vif à la maturation du virus.

Spanish

Campo(s) temático(s)
  • Biotecnología
  • Genética
OBS

Uno de los tres genes auxiliares del VIH [virus de la inmunodeficiencia humana].

Save record 2

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