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XENICAL [1 record]
Record 1 - internal organization data 2023-03-30
Record 1, English
Record 1, Subject field(s)
- Chemical Elements and Compounds
- Medication
- Dietetics
Universal entry(ies) Record 1
Record 1, Main entry term, English
- [(2S)-1-[(2S,3S)-3-hexyl-4-oxo-oxetan-2-yl]tridecan-2-yl] N-formyl-L-leucinate
1, record 1, English, %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
correct, see observation
Record 1, Abbreviations, English
Record 1, Synonyms, English
- orlistat 2, record 1, English, orlistat
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A lipase inhibitor that aids weight loss by reversibly binding to the active center of the enzyme lipase, preventing the digestion and absorption of some dietary fats. 3, record 1, English, - %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
Record number: 1, Textual support number: 1 CONT
Orlistat, when used in conjunction with a mildly hypocaloric diet, is indicated for obesity management including weight loss and weight maintenance. ... Orlistat is indicated for obese patients with a BMI [body mass index] [greater than or equal to] 30 kg/m2 or a BMI [greater than or equal to]27 kg/m2 in the presence of other risk factors (e.g. hypertension, type 2 diabetes, dyslipidemia, excess visceral fat). 4, record 1, English, - %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
Record number: 1, Textual support number: 1 OBS
[(2S)-1-[(2S,3S)-3-hexyl-4-oxo-oxetan-2-yl]tridecan-2-yl] N-formyl-L-leucinate: The capital letter "N-" must be italicized; The letter "L-" is a small capital; form recommended by the IUPAC (International Union of Pure and Applied Chemistry) for the systematic name corresponding to the CAS number indicated on the present record. 1, record 1, English, - %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
Record number: 1, Textual support number: 2 OBS
orlistat: international nonproprietary name (INN). 1, record 1, English, - %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
Record number: 1, Textual support number: 3 OBS
Xenical (Roche): Name under which the active ingredient is sold. 5, record 1, English, - %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
Record number: 1, Textual support number: 4 OBS
Chemical formula: C29H53NO5 5, record 1, English, - %5B%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Doxetan%2D2%2Dyl%5Dtridecan%2D2%2Dyl%5D%20N%2Dformyl%2DL%2Dleucinate
Record 1, French
Record 1, Domaine(s)
- Éléments et composés chimiques
- Médicaments
- Diététique
Entrée(s) universelle(s) Record 1
Record 1, Main entry term, French
- N-formyl-L-leucinate de (2S)-1-[(2S,3S)-3-hexyl-4-oxo-oxétan-2-yl]tridécan-2-yle
1, record 1, French, N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
correct, see observation, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- orlistat 2, record 1, French, orlistat
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Médicament qui agit contre l'obésité en inhibant, dans la lumière du tube digestif, l'activité de la lipase pancréatique, diminuant ainsi l'absorption des graisses. 3, record 1, French, - N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
Record number: 1, Textual support number: 1 CONT
L'orlistat (Xenical). Ce médicament a pour effet d'entraver l'enzyme responsable de l'absorption des graisses dans le tube digestif. Il empêche ainsi l'absorption d'environ 30 % des graisses alimentaires (triglycérides), ce qui équivaut à une réduction calorique de 150 à 200 calories/jour pour un apport journalier de 1800 calories. Les graisses non absorbées sont éliminées dans les selles. 4, record 1, French, - N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
Record number: 1, Textual support number: 1 OBS
N-formyl-L-leucinate de (2S)-1-[(2S,3S)-3-hexyl-4-oxo-oxétan-2-yl]tridécan-2-yle : La lettre majuscule «N-» s'écrit en italique; la lettre «L-» est une petite majuscule; forme recommandée par l'UICPA (Union internationale de chimie pure et appliquée) pour le nom systématique correspondant au numéro CAS indiqué sur la présente fiche. 1, record 1, French, - N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
Record number: 1, Textual support number: 2 OBS
orlistat: dénomination commune internationale (DCI). 1, record 1, French, - N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
Record number: 1, Textual support number: 3 OBS
Xenical (Roche) : Nom sous lequel le principe actif est commercialisé. 5, record 1, French, - N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
Record number: 1, Textual support number: 4 OBS
Formule chimique : C29H53NO5 5, record 1, French, - N%2Dformyl%2DL%2Dleucinate%20de%20%282S%29%2D1%2D%5B%282S%2C3S%29%2D3%2Dhexyl%2D4%2Doxo%2Dox%C3%A9tan%2D2%2Dyl%5Dtrid%C3%A9can%2D2%2Dyle
Record 1, Spanish
Record 1, Textual support, Spanish
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