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AMPLICON [1 record]
Record 1 - internal organization data 2013-07-15
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- amplicon
1, record 1, English, amplicon
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
A CHO cell [Chinese hamster ovary cell] line with a single copy of the DHFR [dihydrofolate reductase] locus on chromosome Z2 was used to analyze the structure of the amplification target and products subsequent to the initial amplification event. Dramatic diversity in the number and cytogenetic characteristics of DHFR amplicons was observed as soon as eight to nine cell doublings following the initial event. 1, record 1, English, - amplicon
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- amplicon
1, record 1, French, amplicon
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
L'amplification est un moyen d'activation de certains proto-oncogènes dans des cancers humains. Qu'elle apparaisse sous forme intra- ou extrachromosomique, la région génomique amplifiée, ou amplicon, semble résulter d'événements initiaux de recombinaison qui pourraient être communs à d'autres types d'altérations génétiques (délétions, translocations). Souvent de grande taille, l'amplicon peut contenir plusieurs gènes adjacents à celui dont l'amplification - et la surexpression - confèrent un avantage sélectif aux cellules qui le portent. 1, record 1, French, - amplicon
Record number: 1, Textual support number: 1 OBS
Tiré du périodique : Genes and Development, 1991, 5 (2), pp. 160-174. 2, record 1, French, - amplicon
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
Record 1, Main entry term, Spanish
- amplicón
1, record 1, Spanish, amplic%C3%B3n
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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