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ANTICUERPO INCOMPLETO [1 record]

Record 1 2006-05-18

English

Subject field(s)
  • Immunology
DEF

Antibody that binds to erythrocytes or bacteria but does not produce agglutination.

CONT

The nonagglutinating antibody is detectable with the antiglobulin (Coombs) test. For example, IgG anti-Rh antibodies do not agglutinate erythrocytes in physiologic saline whereas IgM antibodies do (the large IgM molecule can cross-link the erythrocytes at a wider separation so that there is less electrostatic repulsion due to the zeta potential).

French

Domaine(s)
  • Immunologie
CONT

Un anticorps est dit «agglutinant» (les hématies) quand il entraîne l'hémagglutination en milieu salin (CINa 0,15 mol/l). Dans le cas contraire, on parle d'anticorps «non agglutinant».

CONT

En raison du faible nombre de site antigénique Rhésus [...], le nombre de molécules d'IgG anti-Rhésus fixées sur chaque hématie est insuffisant pour agglutiner les globules rouges : ces anticorps sont improprement appelés «incomplets» par opposition aux IgM anti-Rhésus qui sont agglutinants (anticorps complets).

OBS

anticorps incomplet (impropre). Source : J.-F. Bach, P. Lesavre, Op, Cit., p. 50.

Spanish

Campo(s) temático(s)
  • Inmunología
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