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SRS-A [1 record]

Record 1 2006-05-05

English

Subject field(s)
  • Immunology
DEF

A substance released in the anaphylactic reaction that induces slow, prolonged contraction of certain smooth muscles. It is composed of a mixture of leukotrienes C4, D4 and E4.

French

Domaine(s)
  • Immunologie
DEF

Médiateur chimique libéré, au cours des réactions allergiques de type I et responsable d'une contraction des fibres musculaires lisses plus tardive mais plus prolongée que celle due à l'histamine. Identifié actuellement comme étant un mélange de leucotriènes LTC 4, LTD 4 et LTE 4, provenant du métabolisme de l'acide arachidonique par la voie de la lipo-oxygénase.

CONT

On distingue deux types de leucotriènes, selon qu'ils comportent une chaîne peptidique (LTC4, LTD4, LTE4) ou non (LTB4). Tous [...] sont les constituants de la «slow reacting substance of anaphylaxis» (SRS-A).

Spanish

Campo(s) temático(s)
  • Inmunología
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