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The Government of Canada’s terminology and linguistic data bank.
TARGETING DROGAS [1 record]
Record 1 - internal organization data 2019-10-09
Record 1, English
Record 1, Subject field(s)
- Pharmacodynamics
Record 1, Main entry term, English
- drug targeting
1, record 1, English, drug%20targeting
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
[The process by which] a drug molecule [accumulates] in the target organ or tissue selectively such that the concentration of the drug at the disease site is high, while its concentration in nontarget organs and tissues is low, preferably below a certain minimal level, so as to prevent any toxic effect. 2, record 1, English, - drug%20targeting
Record 1, French
Record 1, Domaine(s)
- Pharmacodynamie
Record 1, Main entry term, French
- ciblage pharmacologique
1, record 1, French, ciblage%20pharmacologique
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- vectorisation de médicament 2, record 1, French, vectorisation%20de%20m%C3%A9dicament
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Action qui consiste à augmenter, à l'aide d'un vecteur, la concentration d'une substance pharmacologiquement active au sein d'un site particulier de l'organisme, l'organe cible, tout en réduisant ses concentrations au sein d'autres sites. 1, record 1, French, - ciblage%20pharmacologique
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Farmacodinámica
Record 1, Main entry term, Spanish
- vectorización de medicamentos
1, record 1, Spanish, vectorizaci%C3%B3n%20de%20medicamentos
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- vectorización de fármacos 2, record 1, Spanish, vectorizaci%C3%B3n%20de%20f%C3%A1rmacos
correct, feminine noun
- conducción de fármacos 3, record 1, Spanish, conducci%C3%B3n%20de%20f%C3%A1rmacos
correct, feminine noun
- dosificación local-dirigida de fármacos 4, record 1, Spanish, dosificaci%C3%B3n%20local%2Ddirigida%20de%20f%C3%A1rmacos
correct, feminine noun, Spain
- targeting de drogas 5, record 1, Spanish, targeting%20de%20drogas
anglicism, masculine noun, Argentina, Uruguay
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
[…] entre las aplicaciones más importantes para el uso de las nanopartículas se encuentra la vectorización de medicamentos hacia el cerebro, […] lo cual puede ayudar en el tratamiento de enfermedades como el Alzheimer o el mal de Parkinson. 6, record 1, Spanish, - vectorizaci%C3%B3n%20de%20medicamentos
Record number: 1, Textual support number: 1 OBS
[…] tradicionalmente [la tarea de] llevar una substancia activa a su diana terapéutica se adjudica a un transportador como la sangre, que tiene [el inconveniente de distribuirla] por todas partes, [debido a que] no elige a sus destinatarios. La idea de la vectorización [consiste en utilizar] la sangre como transporte [e] incluir el fármaco en unas estructuras que, al alcanzar la diana terapéutica, liberan el fármaco que contienen […] 2, record 1, Spanish, - vectorizaci%C3%B3n%20de%20medicamentos
Record number: 1, Textual support number: 2 OBS
Diana terapéutica. Sustancia localizada en cualquier parte de la célula como la membrana celular, el citoplasma o el núcleo, capaz de reconocer un fármaco y producir una respuesta celular […] 7, record 1, Spanish, - vectorizaci%C3%B3n%20de%20medicamentos
Record number: 1, Textual support number: 3 OBS
La vectorización permite la liberación controlada del principio activo y con ello se mantiene una mayor duración de las concentraciones terapéuticas, disminución de sus efectos adversos y menor dosificación del fármaco […] 8, record 1, Spanish, - vectorizaci%C3%B3n%20de%20medicamentos
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