TERMIUM Plus®

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LIQUIDE GASTRIQUE SIMULE [2 records]

Record 1 2010-12-16

English

Subject field(s)
  • Bioengineering
  • Biochemistry
  • Biotechnology
CONT

The prerequisite for glasses and glass-ceramics to bond to living bone is the formation of biologically active bonelike apatite on their surfaces in the body. Our previous study showed that a silica gel prepared by a hydrolysis and polycondensation of tetraethoxysilane in aqueous solution containing poly(ethylene glycol) induces apatite nucleation on its surface in a simulated body fluid. In the present study, the effects of heat treatment of silica gel on its catalytic effects in apatite nucleation was investigated in a simulated body fluid. It was found that apatite forms on the surfaces of silica gels heat-treated below 800 C, but not on those heat-treated above 900 C. The volume of nanometer-range pores in the gel remarkably decreased by heat treatment above 900 C. The concentration of silanol groups in the silica gels gradually decreased with increasing heat treatment temperature. The rate of silica dissolution from the gel into the simulated body fluid decreased remarkably by heat treatment above 900 C. This suggested that a special type of silanol group which is formed by soaking the gel treated below 800 C into the simulated body fluid is responsible for apatite nucleation.

OBS

body fluid: Any liquid component of the body.

French

Domaine(s)
  • Technique biologique
  • Biochimie
  • Biotechnologie
CONT

Les recherches sur les aspects santé et sécurité de la fibre de verre font partie de trois catégories de base : a) les études épidémiologiques humaines évaluent la santé des travailleurs de la fibre de verre; b) les études en laboratoire examinent les effets biologiques de la fibre de verre sur les animaux de laboratoire, les cultures cellulaires et les liquides organiques simulés; c) les études sur l’hygiène industrielle mesurent les expositions à la poussière de fibre de verre en suspension dans l’air pendant la fabrication, l’installation, l’utilisation et l’enlèvement.

OBS

Contrairement aux allergènes protéiques connus, [les protéines CryIA(b) et PAT] sont dégradées rapidement par l’acide ou l’hydrolyse enzymatique lorsqu’elles sont exposées à des liquides gastriques simulés.

OBS

le test du liquide gastrique simulé(LGS), un système artificiel pour tester la digestibilité des protéines, n’ est pas identique aux conditions physiologiques du tube digestif.

OBS

liquide organique : Liquide qui circule dans l’organisme ou est secrété par lui (sang, plasma, lymphe, liquide céphalo-rachidien, urines, sueur, etc.).

Spanish

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Record 2 2002-08-29

English

Subject field(s)
  • Bioengineering
  • Biochemistry
  • Biotechnology
CONT

Important food allergens were stable to digestion in the gastric model (simulated gastric fluid). For example, soybean beta-conglycinin was stable for 60 min. In contrast, nonallergenic food proteins, such as spinach ribulose bis-phosphate carboxylase/oxygenase, were digested in simulated gastric fluid within 15 sec. The data are consistent with the hypothesis that food allergens must exhibit sufficient gastric stability to reach the intestinal mucosa where absorption and sensitization (development of atopy) can occur.

French

Domaine(s)
  • Technique biologique
  • Biochimie
  • Biotechnologie
CONT

On se préoccupe beaucoup des nouvelles méthodes de testage de l'allergénicité et de la toxicité actuellement disponibles. Ainsi, le test du liquide gastrique simulé(LGS), un système artificiel pour tester la digestibilité des protéines, n’ est pas identique aux conditions physiologiques du tube digestif. Ce genre de test ne peut pas toujours donner clairement la preuve des possibilités toxiques ou allergéniques de peptides formés comme des produits de fractionnement dans le système de test.

Spanish

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