TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
PHOSPHORYLATION PROTEINES [6 records]
Record 1 - internal organization data 2011-09-27
Record 1, English
Record 1, Subject field(s)
- Biochemistry
Record 1, Main entry term, English
- phosphorylation
1, record 1, English, phosphorylation
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The esterification of compounds with phosphoric acid. 2, record 1, English, - phosphorylation
Record number: 1, Textual support number: 1 CONT
One such modification [molecular modification of proteins] is phosphorylation, the addition or attachment of a phosphate group. Phosphorylation has a profound effect on the function of proteins. It is commonly stimulated by transmitters and drugs that act via G protein-coupled receptors. 3, record 1, English, - phosphorylation
Record 1, French
Record 1, Domaine(s)
- Biochimie
Record 1, Main entry term, French
- phosphorylation
1, record 1, French, phosphorylation
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- phosphorylisation 2, record 1, French, phosphorylisation
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Réaction chimique comportant la fixation d’un radical phosphoryle sur un composé chimique. 3, record 1, French, - phosphorylation
Record number: 1, Textual support number: 1 CONT
L'une de ces modifications [transformations moléculaires des protéines] est la phosphorylation des protéines, la liaison d’un groupe phosphate, qui modifie notablement la fonction des protéines, et est souvent stimulée par des médiateurs ou par des drogues agissant par l'intermédiaire de facteurs couplés à des protéines G. 4, record 1, French, - phosphorylation
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioquímica
Record 1, Main entry term, Spanish
- fosforilación
1, record 1, Spanish, fosforilaci%C3%B3n
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Proceso metabólico de esterificación de componentes orgánicos con ácido ortofosfórico. 2, record 1, Spanish, - fosforilaci%C3%B3n
Record 2 - internal organization data 2011-08-09
Record 2, English
Record 2, Subject field(s)
- Biological Sciences
Record 2, Main entry term, English
- regulatory subunit
1, record 2, English, regulatory%20subunit
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
The subunit of a regulatory enzyme that has no enzymatic activity but binds the effector. 1, record 2, English, - regulatory%20subunit
Record number: 2, Textual support number: 1 CONT
The aspartate transcarbamoylase of E. coli ... can be dissociated ... to yield two identical catalytic subunits and three identical regulatory subunits.... The mixture retains catalytic activity but the reaction is not inhibited by CTP so long as the catalytic and regulatory subunits are detached from each other. 2, record 2, English, - regulatory%20subunit
Record number: 2, Textual support number: 1 OBS
See "catalytic subunit". 1, record 2, English, - regulatory%20subunit
Record 2, French
Record 2, Domaine(s)
- Sciences biologiques
Record 2, Main entry term, French
- sous-unité régulatrice
1, record 2, French, sous%2Dunit%C3%A9%20r%C3%A9gulatrice
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- sous-unité de régulation 2, record 2, French, sous%2Dunit%C3%A9%20de%20r%C3%A9gulation
correct, feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Sous-unité d’un enzyme allostérique capable de fixer l’effecteur allostérique (mais dépourvue d’activité catalytique). 2, record 2, French, - sous%2Dunit%C3%A9%20r%C3%A9gulatrice
Record number: 2, Textual support number: 1 CONT
La principale action du cAMP dans le métabolisme est de stimuler l'activité des protéines kinases, un groupe d’enzymes qui catalyse la phosphorylation des protéines. [...] L'enzyme possède deux sous-unités : l'une catalytique et l'autre, régulatrice et qui peut lier le cAMP. En absence de cAMP, les sous-unités régulatrice et catalytique forment un complexe enzymatiquement inactif. La liaison du cAMP à la sous-unité régulatrice entraîne un changement conformationnel et dissocie le complexe. La sous-unité catalytique ainsi libérée est enzymatiquement active et elle phosphoryle les autres enzymes. 3, record 2, French, - sous%2Dunit%C3%A9%20r%C3%A9gulatrice
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2010-02-04
Record 3, English
Record 3, Subject field(s)
- Biochemistry
- Molecular Biology
Record 3, Main entry term, English
- protein tyrosine kinase
1, record 3, English, protein%20tyrosine%20kinase
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
[An enzyme that] phosphorylates tyrosine residues in some proteins. 1, record 3, English, - protein%20tyrosine%20kinase
Record 3, French
Record 3, Domaine(s)
- Biochimie
- Biologie moléculaire
Record 3, Main entry term, French
- protéine tyrosine kinase
1, record 3, French, prot%C3%A9ine%20tyrosine%20kinase
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
[L']activation se traduit souvent par la mise en jeu d’une activité protéine tyrosine kinase(c'est-à-dire une activité de phosphorylation de protéines sur une tyrosine) portée par le récepteur ou simplement couplée au récepteur. 1, record 3, French, - prot%C3%A9ine%20tyrosine%20kinase
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2005-08-02
Record 4, English
Record 4, Subject field(s)
- Molecular Biology
- Biochemistry
Record 4, Main entry term, English
- G protein-coupled receptor kinase
1, record 4, English, G%20protein%2Dcoupled%20receptor%20kinase
correct
Record 4, Abbreviations, English
- GRK 1, record 4, English, GRK
correct
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
The G-protein-coupled receptor kinases (GRKs) are protein kinases that phosphorylate only active G-protein-coupled receptors. 2, record 4, English, - G%20protein%2Dcoupled%20receptor%20kinase
Record 4, Key term(s)
- G-protein-coupled receptor kinase
- G protein coupled receptor kinase
Record 4, French
Record 4, Domaine(s)
- Biologie moléculaire
- Biochimie
Record 4, Main entry term, French
- kinase associée au récepteur couplé à une protéine G
1, record 4, French, kinase%20associ%C3%A9e%20au%20r%C3%A9cepteur%20coupl%C3%A9%20%C3%A0%20une%20prot%C3%A9ine%20G
correct, feminine noun
Record 4, Abbreviations, French
- GRK 1, record 4, French, GRK
feminine noun
Record 4, Synonyms, French
- kinase spécifique du récepteur couplé à une protéine G 2, record 4, French, kinase%20sp%C3%A9cifique%20du%20r%C3%A9cepteur%20coupl%C3%A9%20%C3%A0%20une%20prot%C3%A9ine%20G
correct, feminine noun
- kinase du récepteur couplé avec la protéine G 3, record 4, French, kinase%20du%20r%C3%A9cepteur%20coupl%C3%A9%20avec%20la%20prot%C3%A9ine%20G
correct, feminine noun
- KRG 3, record 4, French, KRG
correct, feminine noun
- KRG 3, record 4, French, KRG
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
La phosphorylation du récepteur intervient dès la fixation du ligand. Deux classes principales de protéines kinases sont impliquées dans ce phénomène : la PKA et les GRK. 1, record 4, French, - kinase%20associ%C3%A9e%20au%20r%C3%A9cepteur%20coupl%C3%A9%20%C3%A0%20une%20prot%C3%A9ine%20G
Record number: 4, Textual support number: 2 CONT
Les kinases associées aux récepteurs couplés aux protéines G (GRK) : Le rôle des GRK a été montré par un certain nombre de moyens comme la surexpression, ou l’utilisation d’anticorps inhibant leur fonction. 1, record 4, French, - kinase%20associ%C3%A9e%20au%20r%C3%A9cepteur%20coupl%C3%A9%20%C3%A0%20une%20prot%C3%A9ine%20G
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 1996-03-22
Record 5, English
Record 5, Subject field(s)
- Biochemistry
- Biotechnology
Record 5, Main entry term, English
- protein thyrosin phosphatase
1, record 5, English, protein%20thyrosin%20phosphatase
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
A basis of understanding has been reached with Biosignal Inc. for licensing of PTP (protein thyrosin phosphatase). 1, record 5, English, - protein%20thyrosin%20phosphatase
Record 5, French
Record 5, Domaine(s)
- Biochimie
- Biotechnologie
Record 5, Main entry term, French
- protéine thyrosine phosphatase
1, record 5, French, prot%C3%A9ine%20thyrosine%20phosphatase
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
La phosphorylation des protéines dites d’ancrage est essentielle pour la transmission des signaux cellulaires. Dans cette note, nous démontrons que la mise en culture des thymocytes humains induit la phosphorylation de la protéine thyrosine phosphatase. 1, record 5, French, - prot%C3%A9ine%20thyrosine%20phosphatase
Record number: 5, Textual support number: 1 OBS
Tiré de: Journal : Comptes rendus de l’Académie des sciences. Série 3, Sciences de la vie, 1995, 318, (3) (367-374). 1, record 5, French, - prot%C3%A9ine%20thyrosine%20phosphatase
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 1994-03-22
Record 6, English
Record 6, Subject field(s)
- Cytology
- Genetics
Record 6, Main entry term, English
- protein phosphorylation
1, record 6, English, protein%20phosphorylation
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
There are some questions as to methodology [concerning research in molecular and developmental genetics] Things such as possible difficulties with interpretation of data from using heterologous biochemical assays and correlating in vitro protein phosphorylation sites with in vivo sites of phosphorylation could have been better addressed .... 1, record 6, English, - protein%20phosphorylation
Record number: 6, Textual support number: 2 CONT
Protein kinase C-mediated bidirectional regulation of DNA synthesis, RB protein phosphorylation, and cyclin-dependent kinases in human vascular endothelial cells ... Agents which activate protein kinase C or otherwise enhance protein phosphorylation caused a substantial decrease in A beta production in vitro ... The muscarinic inhibition of cyclic AMP (cAMP) mediated contractile effects may not only be the result of a reduction in cAMP levels, but may also involve cAMP linked protein phosphorylation in the heart ... Recent studies in Alzheimer brains have shown aberrant protein phosphorylation, suggesting an alteration in protein kinases and/or phosphoprotein phosphatases ... [Source: PASCAL database]. 2, record 6, English, - protein%20phosphorylation
Record 6, French
Record 6, Domaine(s)
- Cytologie
- Génétique
Record 6, Main entry term, French
- phosphorylation de protéines
1, record 6, French, phosphorylation%20de%20prot%C3%A9ines
correct, feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
L'exemple le plus ancien et le plus célèbre des régulations par phosphorylation de protéines est celui de la glycogène phosphorylase, déjà rencontrée comme protéine allostérique. Nous savons qu'un 2e mécanisme règle l'activité de la protéine puisqu'elle peut passer par phosphorylation d’une forme b peu active à une forme a très active. Une seule phosphorylation sur chaque sous-unité du dimère suffit [...] 1, record 6, French, - phosphorylation%20de%20prot%C3%A9ines
Record 6, Spanish
Record 6, Textual support, Spanish
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