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SCHIZOPHRENIE REFRACTAIRE [1 record]
Record 1 - internal organization data 2018-06-11
Record 1, English
Record 1, Subject field(s)
- Psychoses
- Clinical Psychology
Record 1, Main entry term, English
- treatment-refractory schizophrenia
1, record 1, English, treatment%2Drefractory%20schizophrenia
correct
Record 1, Abbreviations, English
- TRS 1, record 1, English, TRS
correct
Record 1, Synonyms, English
- treatment-resistant schizophrenia 2, record 1, English, treatment%2Dresistant%20schizophrenia
correct
- TRS 3, record 1, English, TRS
correct
- TRS 3, record 1, English, TRS
- refractory schizophrenia 4, record 1, English, refractory%20schizophrenia
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Between one-third and one-half of the individuals who meet diagnostic criteria for schizophrenia remain actively ill despite optimal pharmacological treatment. ... For patients who do not respond to the first prescribed antipsychotic drug, current clinical practice is to switch to a second and a third drug, and eventually to clozapine, the only antipsychotic drug proven to be effective in treatment-refractory schizophrenia (TRS). 1, record 1, English, - treatment%2Drefractory%20schizophrenia
Record 1, French
Record 1, Domaine(s)
- Psychoses
- Psychologie clinique
Record 1, Main entry term, French
- schizophrénie réfractaire
1, record 1, French, schizophr%C3%A9nie%20r%C3%A9fractaire
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- schizophrénie résistante au traitement 2, record 1, French, schizophr%C3%A9nie%20r%C3%A9sistante%20au%20traitement
correct, feminine noun
- schizophrénie résistante 2, record 1, French, schizophr%C3%A9nie%20r%C3%A9sistante
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Schizophrénie dont les signes et symptômes ne sont pas soulagés par les traitements de premiers recours. 3, record 1, French, - schizophr%C3%A9nie%20r%C3%A9fractaire
Record number: 1, Textual support number: 1 CONT
Commercialisée au début des années 1970, [la clozapine] se positionne comme une troisième ligne dans l'algorithme de traitement après l'échec d’un traitement à l'aide de deux antipsychotiques, dont un atypique, en raison de la gravité de certains effets indésirables [...]. La clozapine permet une réponse clinique chez environ 30 à 60 % des patients atteints de schizophrénie réfractaire [...] 4, record 1, French, - schizophr%C3%A9nie%20r%C3%A9fractaire
Record 1, Spanish
Record 1, Textual support, Spanish
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