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The Government of Canada’s terminology and linguistic data bank.
SUBSTITUTION ACIDE AMINE [3 records]
Record 1 - internal organization data 2004-01-20
Record 1, English
Record 1, Subject field(s)
- Biochemistry
Record 1, Main entry term, English
- trypsin
1, record 1, English, trypsin
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Protease that is secreted by the pancreas of vertebrates in the form of an inactive precursor trypsinogen. 2, record 1, English, - trypsin
Record number: 1, Textual support number: 1 CONT
Proteolytic enzymes and chemical reagents are available that will cleave proteins between specific amino acid residues. The enzyme trypsin, for instance, cuts on the carboxyl side of lysine or arginine residues, whereas the chemical cyanogen bromide cuts peptide bonds next to methionine residues. Since these enzymes and chemicals cleave at relatively few sites in a protein, they tend to produce rather large peptides. 3, record 1, English, - trypsin
Record 1, French
Record 1, Domaine(s)
- Biochimie
Record 1, Main entry term, French
- trypsine
1, record 1, French, trypsine
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Enzyme du suc pancréatique provenant de l’activation de son précurseur (le trypsinogène) sous l’action de l’entérokinase et qui hydrolyse certains polypeptides, jouant ainsi un rôle dans la digestion intestinale des protéines. 2, record 1, French, - trypsine
Record number: 1, Textual support number: 1 CONT
[Un exemple] de synthèse industrielle assurée par des enzymes [...] concerne la conversion en insuline humaine de l'insuline de porc, impossible à réaliser chimiquement, mais aisément catalysée par une enzyme. Dans ce procédé, développé par Novo, la trypsine catalyse la substitution du trentième acide aminé de la chaîne [bêta] de l'insuline de porc, l'alanine, en un autre acide aminé, la thréonine. Le produit obtenu ne peut être distingué de l'insuline humaine. 3, record 1, French, - trypsine
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioquímica
Record 1, Main entry term, Spanish
- tripsina
1, record 1, Spanish, tripsina
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Enzima proteolítica digestiva producida por el páncreas exocrino que cataliza en el intestino delgado la fragmentación de las proteínas de la dieta en peptonas, péptidos y aminoácidos. 2, record 1, Spanish, - tripsina
Record 2 - internal organization data 1980-09-01
Record 2, English
Record 2, Subject field(s)
- Microbiology and Parasitology
Record 2, Main entry term, English
- beta chain 1, record 2, English, beta%20chain
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 OBS
The alpha and beta chains have essentially the same structure, are about the same length and show roughly the same rate of evolutionary amino acid substitution. They arose through gene duplication some 450 million years ago and became differentiated as they accumulated mutations independently. 1, record 2, English, - beta%20chain
Record 2, French
Record 2, Domaine(s)
- Microbiologie et parasitologie
Record 2, Main entry term, French
- chaîne bêta 1, record 2, French, cha%C3%AEne%20b%C3%AAta
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 OBS
Les chaînes alpha et bêta ont approximativement la même structure, sont de longueur à peu près identique et présentent des taux de substitution d’acide aminé voisins. Elles se sont formées, il y a quelque 450 millions d’années, par duplication génique, puis se sont différenciées indépendamment par accumulation de mutations. 1, record 2, French, - cha%C3%AEne%20b%C3%AAta
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 1980-09-01
Record 3, English
Record 3, Subject field(s)
- Microbiology and Parasitology
Record 3, Main entry term, English
- alpha chain 1, record 3, English, alpha%20chain
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 OBS
The alpha and beta chains have essentially the same structure, are about the same length and show roughly the same rate of evolutionary amino acid substitution. They arose through gene duplication some 450 million years ago and became differentiated as they accumulated mutations independently. 1, record 3, English, - alpha%20chain
Record 3, French
Record 3, Domaine(s)
- Microbiologie et parasitologie
Record 3, Main entry term, French
- chaîne alpha 1, record 3, French, cha%C3%AEne%20alpha
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 OBS
Les chaînes alpha et bêta ont approximativement la même structure, sont de longueur à peu près identique et présentent des taux de substitution d’acide aminé voisins. Elles se sont formées, il y a quelque 450 millions d’années, par duplication génique, puis se sont différenciées indépendamment par accumulation de mutations. 1, record 3, French, - cha%C3%AEne%20alpha
Record 3, Spanish
Record 3, Textual support, Spanish
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