TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
TRANSGENE [12 records]
Record 1 - internal organization data 2021-05-19
Record 1, English
Record 1, Subject field(s)
- Biotechnology
- Genetics
- Molecular Biology
Record 1, Main entry term, English
- polymerase chain reaction
1, record 1, English, polymerase%20chain%20reaction
correct
Record 1, Abbreviations, English
- PCR 2, record 1, English, PCR
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The polymerase chain reaction (PCR) is a scientific technique in molecular biology to amplify a single or few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence. 3, record 1, English, - polymerase%20chain%20reaction
Record number: 1, Textual support number: 1 OBS
A technique used to make numerous copies of a DNA segment. 4, record 1, English, - polymerase%20chain%20reaction
Record number: 1, Textual support number: 2 OBS
The method relies on thermal cycling, consisting of cycles of repeated heating and cooling of the reaction for DNA melting and enzymatic replication of the DNA. 3, record 1, English, - polymerase%20chain%20reaction
Record number: 1, Textual support number: 1 PHR
PCR test 4, record 1, English, - polymerase%20chain%20reaction
Record 1, French
Record 1, Domaine(s)
- Biotechnologie
- Génétique
- Biologie moléculaire
Record 1, Main entry term, French
- amplification en chaîne par polymérase
1, record 1, French, amplification%20en%20cha%C3%AEne%20par%20polym%C3%A9rase
correct, feminine noun
Record 1, Abbreviations, French
- PCR 2, record 1, French, PCR
correct, feminine noun
- ACP 3, record 1, French, ACP
correct, feminine noun, rare
Record 1, Synonyms, French
- réaction en chaîne de la polymérase 4, record 1, French, r%C3%A9action%20en%20cha%C3%AEne%20de%20la%20polym%C3%A9rase
correct, feminine noun
- PCR 2, record 1, French, PCR
correct, feminine noun
- RCP 5, record 1, French, RCP
correct, feminine noun
- PCR 2, record 1, French, PCR
- réaction de polymérisation en chaîne 6, record 1, French, r%C3%A9action%20de%20polym%C3%A9risation%20en%20cha%C3%AEne
correct, feminine noun
- PCR 2, record 1, French, PCR
correct, feminine noun
- PCR 2, record 1, French, PCR
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
Technique permettant d’obtenir un grand nombre de copies d’un fragment d’ADN. 6, record 1, French, - amplification%20en%20cha%C3%AEne%20par%20polym%C3%A9rase
Record number: 1, Textual support number: 2 OBS
Pour en isoler l'ADN, l'échantillon subit solubilisation, centrifugation et précipitation par de l'alcool. Le fragment d’ADN constitutif du transgène recherché est alors sélectivement amplifié, c'est-à-dire répliqué en de nombreux exemplaires. [...] on sépare les deux brins formant l'ADN par chauffage [...] puis on introduit dans le milieu de travail des amorces, qui sont les morceaux d’ADN encadrant le transgène. On ajoute aussi une enzyme, par exemple la Taq-polymérase, qui va, à partir des bases placées en excès dans le milieu, fabriquer le brin complémentaire d’ADN. [...] Pour séparer les transgènes des autres portions d’ADN, on pratique alors une électrophorèse, ou migration différentielle sur gel d’agarose. 7, record 1, French, - amplification%20en%20cha%C3%AEne%20par%20polym%C3%A9rase
Record number: 1, Textual support number: 3 OBS
PCR : L’abréviation «PCR» provient du terme anglais «polymerase chain reaction». 6, record 1, French, - amplification%20en%20cha%C3%AEne%20par%20polym%C3%A9rase
Record number: 1, Textual support number: 4 OBS
amplification en chaîne par polymérase; ACP : désignations publiées au Journal officiel de la République française le 23 novembre 2006. 8, record 1, French, - amplification%20en%20cha%C3%AEne%20par%20polym%C3%A9rase
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Biotecnología
- Genética
- Biología molecular
Record 1, Main entry term, Spanish
- reacción en cadena de la polimerasa
1, record 1, Spanish, reacci%C3%B3n%20en%20cadena%20de%20la%20polimerasa
correct, feminine noun
Record 1, Abbreviations, Spanish
- RCP 2, record 1, Spanish, RCP
correct, feminine noun
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Técnica utilizada para hacer copias de moléculas específicas de ADN. 3, record 1, Spanish, - reacci%C3%B3n%20en%20cadena%20de%20la%20polimerasa
Record number: 1, Textual support number: 1 OBS
Se calienta la doble hélice de ADN al objeto de separar sus cadenas. La enzima (junto con las subunidades que conforman el ADN y unas breves secuencias cebadoras) fabrica nuevas copias de la hélice original. El proceso se repite ad infinitum. 3, record 1, Spanish, - reacci%C3%B3n%20en%20cadena%20de%20la%20polimerasa
Record 2 - internal organization data 2019-11-04
Record 2, English
Record 2, Subject field(s)
- Genetics
- Biochemistry
Record 2, Main entry term, English
- endogenous promoter
1, record 2, English, endogenous%20promoter
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- native promoter 2, record 2, English, native%20promoter
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Creating transgenic animals with a [bacterial artificial chromosome] construct can help protect the transgene of interest from endogenous promoters and other regulatory elements ... 1, record 2, English, - endogenous%20promoter
Record 2, French
Record 2, Domaine(s)
- Génétique
- Biochimie
Record 2, Main entry term, French
- promoteur endogène
1, record 2, French, promoteur%20endog%C3%A8ne
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- promoteur natif 2, record 2, French, promoteur%20natif
avoid, calque, masculine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
La création d’animaux transgéniques avec une construction de [chromosomes artificiels bactériens] peut protéger le transgène d’intérêt des promoteurs endogènes et autres éléments de régulation. 1, record 2, French, - promoteur%20endog%C3%A8ne
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2018-02-21
Record 3, English
Record 3, Subject field(s)
- Biotechnology
- Genetics
Record 3, Main entry term, English
- transgenesis
1, record 3, English, transgenesis
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The transfer of genetic material from one organism to another. 2, record 3, English, - transgenesis
Record number: 3, Textual support number: 1 CONT
We determined the expression pattern of the tissue inhibitor of metalloproteinase (TIMP) in the development of the mouse embryo using in situ hybridization and transgenesis. To define the sequences regulating TIMP expression, we generated transgenic mice that expressed the Escherichia coli beta - galactosidase gene under control of a 5' region of the mouse TIMP gene containing -2158 to -58 by upstream of the initiator ATG. 3, record 3, English, - transgenesis
Record 3, French
Record 3, Domaine(s)
- Biotechnologie
- Génétique
Record 3, Main entry term, French
- transgénèse
1, record 3, French, transg%C3%A9n%C3%A8se
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Transfert de matériel génétique d’un organisme à un autre. 2, record 3, French, - transg%C3%A9n%C3%A8se
Record number: 3, Textual support number: 1 CONT
L'introduction d’un gène étranger dans le patrimoine héréditaire d’un individu définit la transgénèse. Différentes techniques sont utilisées chez les mammifères pour y parvenir. Les deux premières ne permettent pas, à elles seules, de choisir l'endroit où le transgène s’intégrera. Il s’agit :(1) de la micro-injection dans l'œuf, qui permet d’introduire de grands fragments d’ADN exogène;(2) des rétrovirus recombinants défectifs qui permettent d’intégrer avec une fréquence élevée des fragments d’ADN dont la taille est cependant limitée par la place disponible dans la capside du rétrovirus. 3, record 3, French, - transg%C3%A9n%C3%A8se
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Biotecnología
- Genética
Record 3, Main entry term, Spanish
- transgénesis
1, record 3, Spanish, transg%C3%A9nesis
correct, feminine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record number: 3, Textual support number: 1 DEF
Transferencia de un gen (que se convierte en transgén) a un organismo receptor (llamado transgénico), que generalmente puede transmitirlo a su descendencia. 2, record 3, Spanish, - transg%C3%A9nesis
Record 4 - internal organization data 2017-07-07
Record 4, English
Record 4, Subject field(s)
- Genetics
Record 4, Main entry term, English
- reporter gene
1, record 4, English, reporter%20gene
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
Transgenic mouse studies have made it possible to define which distant enhancers are necessary for the expression pattern of each of the genes, and to define a new intronic activator that is sufficient for the late expression of a reporter gene. Future experiments will make it possible to define the factors that bind to and are responsible for the activity of this new regulator. 2, record 4, English, - reporter%20gene
Record 4, French
Record 4, Domaine(s)
- Génétique
Record 4, Main entry term, French
- gène rapporteur
1, record 4, French, g%C3%A8ne%20rapporteur
correct, masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 DEF
Gène qui code une protéine détectable in situ et qui, utilisé comme transgène, sert à marquer des cellules dont on veut suivre le devenir, à confirmer l'expression d’un autre transgène ou à évaluer la puissance d’un promoteur. 2, record 4, French, - g%C3%A8ne%20rapporteur
Record number: 4, Textual support number: 1 CONT
Des études faites avec des souris transgéniques ont permis de définir les activateurs nécessaires à l’expression correcte de chacun des transcrits, et de définir un nouvel activateur intronique suffisant pour l’expression tardive d’un gène rapporteur. Des expériences en cours permettront de définir les facteurs qui se lient et qui sont responsables de l’activité de ce nouvel élément régulateur. 3, record 4, French, - g%C3%A8ne%20rapporteur
Record number: 4, Textual support number: 1 OBS
gène rapporteur : terme et définition publiés au Journal officiel de la République française le 14 juin 2017. 4, record 4, French, - g%C3%A8ne%20rapporteur
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Genética
Record 4, Main entry term, Spanish
- gen indicador
1, record 4, Spanish, gen%20indicador
masculine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2016-11-07
Record 5, English
Record 5, Subject field(s)
- Biological Sciences
- Biotechnology
Record 5, Main entry term, English
- reserve protein
1, record 5, English, reserve%20protein
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
- storage protein 2, record 5, English, storage%20protein
correct
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
Storage proteins serve as reserves of metal ions and amino acids, which can be mobilized and utilized for the maintenance and growth of organisms. They are particularly prevalent in plant seeds, egg whites, and milk. 3, record 5, English, - reserve%20protein
Record number: 5, Textual support number: 2 CONT
Globulins is a group of global proteins that are generally insoluble in water and present in blood, eggs, milk, and as a reserve protein in seeds. 4, record 5, English, - reserve%20protein
Record number: 5, Textual support number: 1 OBS
storage protein: term extracted from the “Glossaire de l’agriculture” and reproduced with permission of the Organisation for Economic Co-operation and Development. 5, record 5, English, - reserve%20protein
Record 5, French
Record 5, Domaine(s)
- Sciences biologiques
- Biotechnologie
Record 5, Main entry term, French
- protéine de réserve
1, record 5, French, prot%C3%A9ine%20de%20r%C3%A9serve
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Si le transgène code pour un allergène connu, il est tout à fait probable que la plante transgénique obtenue va exprimer la protéine exogène avec son potentiel allergénique. C'est ce qui s’est passé lorsque la société américaine Pioneer Hi Bred a voulu intégrer dans le soja l'albumine 2S de la noix du Brésil. C'est une protéine de réserve riche en méthionine et cystéine dont l'introduction dans le soja visait à rééquilibrer la composition protéique de la graine(naturellement pauvre en acides aminés soufrés) et donc à augmenter la valeur biologique du soja pour l'alimentation animale. 2, record 5, French, - prot%C3%A9ine%20de%20r%C3%A9serve
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Ciencias biológicas
- Biotecnología
Record 5, Main entry term, Spanish
- proteína de reserva
1, record 5, Spanish, prote%C3%ADna%20de%20reserva
correct, feminine noun
Record 5, Abbreviations, Spanish
Record 5, Synonyms, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2011-10-31
Record 6, English
Record 6, Subject field(s)
- Biotechnology
Record 6, Main entry term, English
- resident gene
1, record 6, English, resident%20gene
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
Because recombination in yeast is primarily legitimate rather than illegitimate, it is relatively easy to replace a resident gene with whatever modified gene that you wish. For E. Coli and yeast, such replacement can be done with ease. With mouse, it is possible but very time consuming to do such replacement. For other organisms, it is not yet possible. 1, record 6, English, - resident%20gene
Record 6, French
Record 6, Domaine(s)
- Biotechnologie
Record 6, Main entry term, French
- gène résident
1, record 6, French, g%C3%A8ne%20r%C3%A9sident
correct, masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
[...] des chercheurs de l'Inra ont introduit dans le tabac le gène de la nitrate réductase(NR) sous le contrôle du promoteur 35S, afin d’optimiser l'assimilation du nitrate absorbé dans la surexpression de cette enzyme. [...] Cette fois encore, il y a eu cosuppression du transgène et du gène résident de la NR. 1, record 6, French, - g%C3%A8ne%20r%C3%A9sident
Record 6, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2011-10-27
Record 7, English
Record 7, Subject field(s)
- Biochemistry
- Molecular Biology
- Plant Biology
Record 7, Main entry term, English
- virus-induced gene silencing 1, record 7, English, virus%2Dinduced%20gene%20silencing
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record 7, Key term(s)
- virus induced gene silencing
Record 7, French
Record 7, Domaine(s)
- Biochimie
- Biologie moléculaire
- Biologie végétale
Record 7, Main entry term, French
- inactivation génique par virus
1, record 7, French, inactivation%20g%C3%A9nique%20par%20virus
correct, feminine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 DEF
Phénomène par lequel un gène, ou un transgène, est inactivé par un virus recombiné comportant une partie de sa séquence. 1, record 7, French, - inactivation%20g%C3%A9nique%20par%20virus
Record number: 7, Textual support number: 1 OBS
L’inactivation génique par virus n’a été observée que dans le monde végétal. 1, record 7, French, - inactivation%20g%C3%A9nique%20par%20virus
Record number: 7, Textual support number: 2 OBS
inactivation génique par virus : terme et définition publiés au Journal officiel de la République française le 18 septembre 2011. 2, record 7, French, - inactivation%20g%C3%A9nique%20par%20virus
Record 7, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 1997-05-14
Record 8, English
Record 8, Subject field(s)
- Biotechnology
Record 8, Main entry term, English
- cellular targetting
1, record 8, English, cellular%20targetting
correct
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record number: 8, Textual support number: 1 CONT
cDNAs such as FLXPER1 and FLXPER2 will be valuable in examining correlations between cell wall associated peroxidase activities and stem lignification, and factors involved with expression, tissue localisation, intracellular targetting and secretion. The impact of lignification processes on commercially and agronomically important characteristics of flax, of which over 0.5 million hectares are grown annually in Canada, can now be tackled with clones such as these. 2, record 8, English, - cellular%20targetting
Record 8, French
Record 8, Domaine(s)
- Biotechnologie
Record 8, Main entry term, French
- ciblage cellulaire
1, record 8, French, ciblage%20cellulaire
correct, masculine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 CONT
De façon générale, le ciblage cellulaire devrait pouvoir bénéficier de l'utilisation de vecteurs où le transgène est sous le contrôle transcriptionnel de promoteurs spécifiques des types cellulaires adéquats, en particulier de son propre promoteur, même si ce dernier est faible. 1, record 8, French, - ciblage%20cellulaire
Record 8, Spanish
Record 8, Textual support, Spanish
Record 9 - internal organization data 1996-08-14
Record 9, English
Record 9, Subject field(s)
- Biotechnology
Record 9, Main entry term, English
- spleen focus forming virus
1, record 9, English, spleen%20focus%20forming%20virus
correct
Record 9, Abbreviations, English
- SFFV 2, record 9, English, SFFV
correct
Record 9, Synonyms, English
Record 9, Textual support, English
Record 9, French
Record 9, Domaine(s)
- Biotechnologie
Record 9, Main entry term, French
- SFFV
1, record 9, French, SFFV
correct, masculine noun
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 CONT
L'expression d’un transgène étant limitée au spectre d’expression du promoteur viral dans les vecteurs classiques, le groupe W. Ostertag a développé l'étude comparative de vecteurs rétroviraux dérivés d’autres types de rétrovirus murins comme le SFFV(spleen focus forming virus), le MESV(murine erythroleukemia virus) ou le MHSV(murine Harvey sarcoma virus). 1, record 9, French, - SFFV
Record 9, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 1996-08-14
Record 10, English
Record 10, Subject field(s)
- Biotechnology
Record 10, Main entry term, English
- murine erythroleukemia virus
1, record 10, English, murine%20erythroleukemia%20virus
correct
Record 10, Abbreviations, English
- MESV 2, record 10, English, MESV
correct
Record 10, Synonyms, English
Record 10, Textual support, English
Record 10, French
Record 10, Domaine(s)
- Biotechnologie
Record 10, Main entry term, French
- MESV
1, record 10, French, MESV
correct, masculine noun
Record 10, Abbreviations, French
Record 10, Synonyms, French
Record 10, Textual support, French
Record number: 10, Textual support number: 1 CONT
L'expression d’un transgène étant limitée au spectre d’expression du promoteur viral dans les vecteurs classiques, le groupe W. Ostertag a développé l'étude comparative de vecteurs rétroviraux dérivés d’autres types de rétrovirus murins comme le SFFV(spleen focus forming virus), le MESV(murine erythroleukemia virus) ou le MHSV(murine Harvey sarcoma virus). 1, record 10, French, - MESV
Record 10, Spanish
Record 10, Textual support, Spanish
Record 11 - internal organization data 1996-08-14
Record 11, English
Record 11, Subject field(s)
- Biotechnology
Record 11, Main entry term, English
- murine Harvey sarcoma virus
1, record 11, English, murine%20Harvey%20sarcoma%20virus
correct
Record 11, Abbreviations, English
Record 11, Synonyms, English
Record 11, Textual support, English
Record 11, French
Record 11, Domaine(s)
- Biotechnologie
Record 11, Main entry term, French
- MHSV
1, record 11, French, MHSV
correct, masculine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
Record 11, Textual support, French
Record number: 11, Textual support number: 1 CONT
L'expression d’un transgène étant limitée au spectre d’expression du promoteur viral dans les vecteurs classiques, le groupe W. Ostertag a développé l'étude comparative de vecteurs rétroviraux dérivés d’autres types de rétrovirus murins comme le SFFV(spleen focus forming virus), le MESV(murine erythroleukemia virus) ou le MHSV(murine Harvey sarcoma virus). 1, record 11, French, - MHSV
Record 11, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 1996-06-13
Record 12, English
Record 12, Subject field(s)
- Genetics
- Molecular Biology
Record 12, Main entry term, English
- heteropolymeric
1, record 12, English, heteropolymeric
correct, adjective
Record 12, Abbreviations, English
Record 12, Synonyms, English
Record 12, Textual support, English
Record number: 12, Textual support number: 1 DEF
Composed of dissimilar constituent building units as a macromolecule, e.g., a protein. 1, record 12, English, - heteropolymeric
Record 12, French
Record 12, Domaine(s)
- Génétique
- Biologie moléculaire
Record 12, Main entry term, French
- hétéropolymérique
1, record 12, French, h%C3%A9t%C3%A9ropolym%C3%A9rique
correct, adjective
Record 12, Abbreviations, French
Record 12, Synonyms, French
Record 12, Textual support, French
Record number: 12, Textual support number: 1 CONT
[Dans le cas de thérapie génique et pour ne pas risquer de voir apparaître une nouvelle symptomatologie]. Cette dernière éventualité(risquer de voir apparaître une nouvelle symptomatologie) est à prendre en considération lorsque le gène muté code pour une sous-unité d’une protéine hétéropolymérique, puisque la quantité de sous-unités non intéressées par la mutation constitue alors un facteur limitant; l'hyperexpression du transgène thérapeutique pourrait donc faire apparaître un excès de formes homopolymériques anormales toxiques pour la cellule. 1, record 12, French, - h%C3%A9t%C3%A9ropolym%C3%A9rique
Record 12, Spanish
Record 12, Textual support, Spanish
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