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TYROSINE KINASE [8 records]
Record 1 - internal organization data 2011-11-02
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- insulin-receptor substrate 1
1, record 1, English, insulin%2Dreceptor%20substrate%201
correct
Record 1, Abbreviations, English
- IRS1 2, record 1, English, IRS1
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
In mammals, one major insulin receptor substrate (IRS1) has been identified as a docking protein which, following tyrosine phosphorylation, is able to interact with several intracellular proteins which, in a cascade, activate most of, if not all, the metabolic and mitogenic pathways controlled by insulin. 3, record 1, English, - insulin%2Dreceptor%20substrate%201
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- substrat 1 du récepteur de l'insuline
1, record 1, French, substrat%201%20du%20r%C3%A9cepteur%20de%20l%27insuline
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Le récepteur [...] IGF1 est une tyrosine kinase dont le substrat principal est un peptide cytoplasmique désigné IRS1(insulin-receptor substrate-1] parce qu'il est également substrat du récepteur de l'insuline. 1, record 1, French, - substrat%201%20du%20r%C3%A9cepteur%20de%20l%27insuline
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2010-02-04
Record 2, English
Record 2, Subject field(s)
- Biochemistry
- Molecular Biology
Record 2, Main entry term, English
- protein tyrosine kinase
1, record 2, English, protein%20tyrosine%20kinase
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
[An enzyme that] phosphorylates tyrosine residues in some proteins. 1, record 2, English, - protein%20tyrosine%20kinase
Record 2, French
Record 2, Domaine(s)
- Biochimie
- Biologie moléculaire
Record 2, Main entry term, French
- protéine tyrosine kinase
1, record 2, French, prot%C3%A9ine%20tyrosine%20kinase
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
[L']activation se traduit souvent par la mise en jeu d’une activité protéine tyrosine kinase(c'est-à-dire une activité de phosphorylation de protéines sur une tyrosine) portée par le récepteur ou simplement couplée au récepteur. 1, record 2, French, - prot%C3%A9ine%20tyrosine%20kinase
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2010-02-04
Record 3, English
Record 3, Subject field(s)
- Biochemistry
- Molecular Biology
Record 3, Main entry term, English
- receptor tyrosine kinase
1, record 3, English, receptor%20tyrosine%20kinase
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
[A receptor that] binds protein tyrosine kinase enzymes such as the receptors for epidermal growth factor, insulin, insulin-like growth factor-1, platelet-derived growth factor, fibroblast growth factor... 1, record 3, English, - receptor%20tyrosine%20kinase
Record 3, French
Record 3, Domaine(s)
- Biochimie
- Biologie moléculaire
Record 3, Main entry term, French
- récepteur tyrosine kinase
1, record 3, French, r%C3%A9cepteur%20tyrosine%20kinase
correct
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Le récepteur de l'insuline est un récepteur tyrosine kinase. C'est une protéine enzymatique, une protéine tyrosine kinase, sur laquelle se fixe l'insuline : cette enzyme a pour fonction de phosphoryler des résidus tyrosine spécifiques appartenant à d’autres protéines. 1, record 3, French, - r%C3%A9cepteur%20tyrosine%20kinase
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2006-05-08
Record 4, English
Record 4, Subject field(s)
- Biochemistry
- Molecular Biology
Record 4, Main entry term, English
- tyrosine kinase
1, record 4, English, tyrosine%20kinase
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
the EGF receptor tyrosine kinase is an enzyme commonly studied for functions it performs as an internal cell communicator. 2, record 4, English, - tyrosine%20kinase
Record 4, Key term(s)
- tyrosine kinase messenger
Record 4, French
Record 4, Domaine(s)
- Biochimie
- Biologie moléculaire
Record 4, Main entry term, French
- tyrosine-kinase
1, record 4, French, tyrosine%2Dkinase
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
- tyrosine kinase 2, record 4, French, tyrosine%20kinase
correct, feminine noun
- tyrosinekinase 3, record 4, French, tyrosinekinase
correct, feminine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Les récepteurs de croissance possédant une activité intrinsèque de tyrosine kinase s’associent au niveau de leur domaine cytoplasmique à d’autres protéines participant au transfert de signaux mitogéniques. 4, record 4, French, - tyrosine%2Dkinase
Record number: 4, Textual support number: 1 OBS
Tyrosine : acide aminé 5, record 4, French, - tyrosine%2Dkinase
Record number: 4, Textual support number: 2 OBS
terme français formulé d’après les règles généralement suivies dans la nomenclature des enzymes. 1, record 4, French, - tyrosine%2Dkinase
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Bioquímica
- Biología molecular
Record 4, Main entry term, Spanish
- tirosina cinasa
1, record 4, Spanish, tirosina%20cinasa
correct, feminine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2001-09-14
Record 5, English
Record 5, Subject field(s)
- Immunology
Record 5, Main entry term, English
- cell-surface marker
1, record 5, English, cell%2Dsurface%20marker
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
An antigenic determinant occurring on the surface of a specific type of cell. 1, record 5, English, - cell%2Dsurface%20marker
Record 5, French
Record 5, Domaine(s)
- Immunologie
Record 5, Main entry term, French
- marqueur de surface
1, record 5, French, marqueur%20de%20surface
correct, masculine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Un nouveau marqueur de surface des cellules du sang [...] À partir d’un nouveau gène cloné dans les leucocytes de patients atteints d’anémie hémolytique, et qui est homologue à un récepteur tyrosine kinase, développement d’un anticorps contre un marqueur de surface capable de distinguer une population leucocytaire ou érythroïde spécifique pour les anémies et les leucémies. 1, record 5, French, - marqueur%20de%20surface
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2001-04-09
Record 6, English
Record 6, Subject field(s)
- Cytology
- Biochemistry
Record 6, Main entry term, English
- GTPase activating protein
1, record 6, English, GTPase%20activating%20protein
correct
Record 6, Abbreviations, English
- GAP 2, record 6, English, GAP
correct
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
A cytoplasmic protein has been identified that the guanosine triphosphatase (GTPase inhibiting protein is able to counteract the activity of GTPase activating protein (GAP), which has been postulated to function as a negative regulator of Ras activity. The potential biological importance of the GTPase inhibiting protein is further supported by its interaction with lipids. 2, record 6, English, - GTPase%20activating%20protein
Record number: 6, Textual support number: 1 OBS
Tiré de: Science, 1990, 250 (4983), 982-985. 2, record 6, English, - GTPase%20activating%20protein
Record 6, French
Record 6, Domaine(s)
- Cytologie
- Biochimie
Record 6, Main entry term, French
- protéine activant la GTPase
1, record 6, French, prot%C3%A9ine%20activant%20la%20GTPase
correct, feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
Le troisième substrat de l'activité tyrosine kinase du récepteur du PDGF serait la protéine activant la GTPase(GTPase activating protein) qui interagit spécifiquement avec les protéines p 21 ras. 1, record 6, French, - prot%C3%A9ine%20activant%20la%20GTPase
Record 6, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 1993-03-19
Record 7, English
Record 7, Subject field(s)
- Biochemistry
Record 7, Main entry term, English
- neu
1, record 7, English, neu
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 CONT
... developments in molecular oncology have permitted the definition of alterations in proto-oncogenes (ras, myc, neu and hst/int.2) and anti-oncogenes (Rb.1) in human breast carcinomas. (Cited in MEDLINE data base.) 1, record 7, English, - neu
Record 7, French
Record 7, Domaine(s)
- Biochimie
Record 7, Main entry term, French
- neu
1, record 7, French, neu
correct
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 CONT
Nous avons étudié le mécanisme d’activation de l'oncogène c. erbB2 neu, qui appartient à la famille des récepteurs à l'activité tyrosine kinase.(Relevé dans la base de données PASCAL.) 1, record 7, French, - neu
Record 7, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 1991-06-06
Record 8, English
Record 8, Subject field(s)
- Genetics
Record 8, Main entry term, English
- mitogenic signal
1, record 8, English, mitogenic%20signal
proposal
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record 8, French
Record 8, Domaine(s)
- Génétique
Record 8, Main entry term, French
- signal mitogénique
1, record 8, French, signal%20mitog%C3%A9nique
correct, masculine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 CONT
Les récepteurs de facteur de croissance possédant une activité intrinsèque de tyrosine kinase s’associent au niveau de leur domaine cytoplasmique à d’autres protéines participant au transfert des signaux mitogéniques. 1, record 8, French, - signal%20mitog%C3%A9nique
Record 8, Spanish
Record 8, Textual support, Spanish
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