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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 OBS

Since June 2018, the Correctional Service of Canada (CSC) has been rolling out a Prison Needle Exchange Program (PNEP) in federal institutions across the country to help prevent the sharing of needles among inmates and the spread of infectious diseases, such as HIV/AIDS and HCV [hepatitis C virus].  1, record 1, English, - Prison%20Needle%20Exchange%20Program

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 OBS

Depuis juin 2018, le Service correctionnel du Canada(SCC) met en œuvre un Programme d’échange de seringues dans les prisons(PESP) dans les établissements fédéraux partout au pays pour aider à prévenir le partage d’aiguilles entre détenus et la propagation de maladies infectieuses, comme le VIH/sida et le VHC [virus de l'hépatite C].  1, record 1, French, - Programme%20d%27%C3%A9change%20de%20seringues%20dans%20les%20prisons

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

The needlestick accident occurred when the nurse was obtaining a blood sample from a patient who had undergone liver transplantation to treat HCV [hepatitis C virus]-associated cirrhosis. The accident occurred when the nurse's fingertip hit the tip of the needle, which punctured her skin and caused a superficial wound of approximately 2-3 mm that bled spontaneously.  1, record 2, English, - needlestick%20accident

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Le VHB [virus de l'hépatite B] et le VHC [virus de l'hépatite C] sont transmis par le partage d’équipement d’injection souillé [et] par les accidents de piqûre d’aiguille ou autres expositions professionnelles [...]  1, record 2, French, - accident%20de%20piq%C3%BBre%20d%27aiguille

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

The purpose of the serology laboratory is to diagnose infectious diseases by observing the presence of an immune antibody in the patient, which has resulted from infection or entry by the pathogen (i.e. antigen) into the body.  1, record 3, English, - serology%20laboratory

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Le boratoire de sérologie a pour but de rechercher les anticorps produits par le donneur à la suite du contact d’un agent pathogène(VIH, VHC, VHB, HTLV, CMV, Paludisme) et les anticorps anti-HBs. Ces anticorps sont recherchés par des tests immunoenzymatiques(ELISA, IF, Western-Blot, EIA...).  1, record 3, French, - laboratoire%20de%20s%C3%A9rologie

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

[The] document is directed toward physicians and other health-care providers involved in the field of sports medicine and is intended to serve as a guideline to 1) understand HIV and other blood-borne pathogens as they relate to sports; 2) implement practical preventive measures that further minimize the low risk of transmission of these pathogens. 3) develop effective educational initiatives regarding these infections, their transmission, and prevention among athletes and others involved in sports; and 4) provide guidance for the care of HIV-infected athletes.  1, record 4, English, - blood%2Dborne%20pathogen

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Virus présent dans le sang humain qui peut provoquer une infection.  1, record 4, French, - pathog%C3%A8ne%20%C3%A0%20diffusion%20h%C3%A9matog%C3%A8ne

Record number: 4, Textual support number: 1 OBS

Exemples de pathogènes à diffusion hématogène : le virus de l'hépatite B(VHB), le virus de l'hépatite C(VHC) et le virus de l'immunodéficience humaine(VIH).  1, record 4, French, - pathog%C3%A8ne%20%C3%A0%20diffusion%20h%C3%A9matog%C3%A8ne

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

From the estimations of change/mutation rates amongst the different strains of hepatitis C it is estimated that the main genotypes diverged from the original strain at least several thousand years ago with the emergence of the subtypes 200-400 years ago.  2, record 5, English, - original%20strain

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

La variabilité génomique du VHC [virus de l'hépatite C] se caractérise à l'échelle du patient individuel par une hétérogénéité des populations virales dérivant d’une même souche originelle, hétérogénéité dont le degré varie au cours du temps, aboutissant au concept de quasi-espèces.  1, record 5, French, - souche%20originelle

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

Anyone who donates his or her blood to a blood bank or directly to another person.  3, record 6, English, - blood%20donor

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

La découverte d’une sérologie du VHC positive chez un donneur de sang, de tissu ou d’organe impose la confirmation du test. Elle constitue une contre-indication définitive au don. L'information du donneur de sang est obligatoire.  3, record 6, French, - donneur%20de%20sang

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

The protein kinase PKR is a component of the interferon-induced anti-viral defense mechanism in mammalian cells. Upon activation by binding double-stranded RNA in infected cells, the kinase down-regulates the cellular translational apparatus, and thus impairs viral protein expression. To overcome the inhibitory effects of PKR, viruses have developed efficient methods to prevent the activation or function of the kinase. A potential site of therapeutic intervention is to block viral inhibition of PKR.  2, record 7, English, - protein%20kinase%20PKR

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

Récemment, Michael Lai et son équipe de l'université de Los Angeles ont décrit un mécanisme expliquant la plus grande résistance de certaines souches de VHC à l'interféron. Ces chercheurs travaillent sur une enzyme, la protéine kinase PKR, qui fait avorter les virus en inhibant leur synthèse protéique. L'interféron accélère la production de la PKR par les cellules.  1, record 7, French, - prot%C3%A9ine%20kinase%20PKR

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 OBS

HCV: hepatitis C virus.  2, record 8, English, - Transfused%20HCV%20Plan

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 OBS

Source(s) : Division de l’hépatite C, Santé Canada.  1, record 8, French, - R%C3%A9gime%20%C3%A0%20l%27intention%20des%20transfus%C3%A9s%20infect%C3%A9s%20par%20le%20VHC

Record number: 8, Textual support number: 2 OBS

VHC : virus de l'hépatite C.  2, record 8, French, - R%C3%A9gime%20%C3%A0%20l%27intention%20des%20transfus%C3%A9s%20infect%C3%A9s%20par%20le%20VHC

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 OBS

HCV: hepatitis C virus.  2, record 9, English, - Hemophiliac%20HCV%20Plan

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 OBS

VHC : virus de l'hépatite C.  2, record 9, French, - R%C3%A9gime%20%C3%A0%20l%27intention%20des%20h%C3%A9mophiles%20infect%C3%A9s%20par%20le%20VHC

Record number: 9, Textual support number: 2 OBS

Source(s) : Division de l’hépatite C, Santé Canada.  1, record 9, French, - R%C3%A9gime%20%C3%A0%20l%27intention%20des%20h%C3%A9mophiles%20infect%C3%A9s%20par%20le%20VHC

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 DEF

Hepatitis in humans apparently caused by an as-yet uncharacterized retrovirus or retrovirus-like agent. Diagnosis continues to depend on serological exclusion of hepatitis A and B viruses, cytomegalovirus, and Epstein-Barr virus.  1, record 10, English, - non%2DA%2C%20non%2DB%20hepatitis

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 DEF

Hépatite, souvent post-transfusionnelle, au cours desquelles les recherches des virus A et B sont négatives.  2, record 10, French, - h%C3%A9patite%20non%20A%2Dnon%20B

Record number: 10, Textual support number: 1 CONT

Jusqu'à leur découverte en 1989 et en 1990, les virus VHC et VHE étaient classés parmi les hépatites non-A non B(NANB).  3, record 10, French, - h%C3%A9patite%20non%20A%2Dnon%20B

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

Studies continue to suggest that up to 40% of patients with chronic HCV [hepatitis C virus] infection have had no identifiable parenteral exposure, and the mode of transmission in these cases remains poorly established.  1, record 11, English, - chronic%20HCV%20infection

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 CONT

Les AST [aspartate aminotransférase] ou les ALT [alanine aminotransférase] sont également utiles pour surveiller l'évolution de certaines maladies et aident à évaluer la nécessité du traitement ou la réponse au traitement(par exemple, le traitement avec les stéroïdes en cas d’hépatite chronique active auto-immune ou avec l'interféron en cas d’infection chronique par le VHC [virus de l'hépatite C]).  1, record 11, French, - infection%20chronique%20par%20le%20VHC

Record 11,  Textual support,  Spanish