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ANEMIE SIDEROBLASTIQUE [4 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2019-01-16

English

Subject field(s)
  • Human Diseases - Various
  • Blood
Universal entry(ies)
D51.0
classification system code, see observation
DEF

A ... megaloblastic anemia usually seen in older adults, caused by impaired intestinal absorption of vitamin B12 due to [a defective production of] intrinsic factor [by the gastric mucosa].

OBS

D51.0: code used in the International Statistical Classification of Diseases and Related Health Problems.

Key term(s)
  • pernicious anaemia
  • Addison's anaemia
  • addisonian anaemia
  • Biermer's anaemia
  • vitamin B-12 deficiency anemia due to intrinsic factor deficiency
  • vitamin B-12 deficiency anaemia due to intrinsic factor deficiency

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
Entrée(s) universelle(s)
D51.0
classification system code, see observation
DEF

Anémie sidéroblastique macrocytaire par carence en vitamine B12 due à un tarissement de la sécrétion du facteur intrinsèque par l'estomac empêchant l'absorption de la vitamine B12.

OBS

D51.0 : code de la Classification statistique internationale des maladies et des problèmes de santé connexes

Key term(s)
  • anémie par carence en vitamine B-12 due à une carence en facteur intrinsèque

Spanish

Campo(s) temático(s)
  • Enfermedades humanas varias
  • Sangre
Entrada(s) universal(es)
D51.0
classification system code, see observation
DEF

Enfermedad derivada de la carencia de una sustancia esencial para la absorción de vitamina B12 y la maduración de hematíes y otras células sanguíneas, en la que una reducción del número de células sanguíneas afecta a los sistemas gastrointestinal y neurológico.

Save record 1

Record 2 2014-04-07

English

Subject field(s)
  • Human Diseases - Various
  • Blood
CONT

The morphologic features of idiopathic refractory sideroblastic anemia (IRSA) are similar to those described for refractory anemia except for the presence of 15% or more ringed sideroblasts.

OBS

Too few red blood cells in the blood and anemia is present. ... 15% or more of the red blood cells have too much iron (called ringed sideroblasts). ... Normal number of white blood cells and platelets. ... Accounts for approximately 10–12% of MDS [myelodysplastic syndromes] cases. ... Approximately 1–2% of cases transform into AML [acute myelogenous leukemia].

Key term(s)
  • idiopathic refractory sideroblastic anaemia
  • refractory anaemia with ringed sideroblasts

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
CONT

Il y a trop peu de globules rouges dans le sang et présence d’anémie. [...] 15 % ou plus des globules rouges contiennent trop de fer (sidéroblastes en couronne, ou SC). [...] Le nombre de globules blancs et de plaquettes dans le sang est normal. [...] L’ARSI représente environ 10 à 12 % des cas de SMD [syndromes myélodysplasiques]. [...] Environ 1 à 2 % des cas d’ARSI se transforment en LAM [leucémie aiguë myéloblastique].

Spanish

Save record 2

Record 3 2014-04-07

English

Subject field(s)
  • Cytology
  • Blood
CONT

Ring sideroblasts are erythroblasts with iron-loaded mitochondria visualized by Prussian blue staining (Perls’ reaction) as a perinuclear ring of blue granules. ... The International Working Group on Morphology of Myelodysplastic Syndrome (IWGM-MDS) recommended that ring sideroblasts be defined as erythroblasts in which there are a minimum of five siderotic granules covering at least one third of the circumference of the nucleus. Ring sideroblasts are found exclusively in pathological conditions, and should not be confused with ferritin sideroblasts, which are present in normal bone marrow. ... While the iron of ferritin sideroblasts is stored in cytosolic ferritin, whose subunits are encoded by the FTH1 and FTL genes, the iron of ring sideroblasts is stored in mitochondrial ferritin, encoded by the FTMT gene.

French

Domaine(s)
  • Cytologie
  • Sang
CONT

Quand [un] excès de fer se localise aux mitochondries, témoin d’une perturbation de la synthèse d’hémoglobine, et que ces mitochondries viennent se localiser autour du noyau, visibles à la coloration de Perls sous la forme de granulations colorées par le bleu de Prusse et disposées sur au moins un tiers du pourtour nucléaire, on définit le sidéroblaste en couronne, caractéristique nécessaire à la définition d’une anémie sidéroblastique.

Spanish

Save record 3

Record 4 2012-01-31

English

Subject field(s)
  • Blood
DEF

Anemia characterized by the presence of erythroblasts containing excessive deposits of iron in the marrow.

French

Domaine(s)
  • Sang
DEF

Anémie caractérisée principalement par des sidéroblastes; érythrocytes contenant des grains de fer mitochondriaux.

Spanish

Save record 4

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