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CD4 SOLUBLE [6 records]
Record 1 - internal organization data 2012-05-01
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- TAT transdominant inhibitor
1, record 1, English, TAT%20transdominant%20inhibitor
proposal
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- inhibiteur transdominant de TAT
1, record 1, French, inhibiteur%20transdominant%20de%20TAT
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Chaque étape du cycle viral peut constituer une cible d’intervention antiviral. Les agent antiviraux en évaluation dans le monde sont :CD4 soluble, anticorps anti-Env intracellulaires ou secrétés, ribozymes, anticorps intracellulaires antiscriptase inverse(anti-RTase) IFN, leurres de séquence TAR, cible de TAT, inhibiteurs transdominants de TAT, leurres de la séquence RRE de réponse à REV, ARN antisens, inhibiteurs transdominants GAG, CD4 intracellulaires, anticorps anti-ENV "suicide-induit". 1, record 1, French, - inhibiteur%20transdominant%20de%20TAT
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
Record 1, Main entry term, Spanish
- inhibidor transdominante del Tat
1, record 1, Spanish, inhibidor%20transdominante%20del%20Tat
masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2010-04-20
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- Rev Responsive Element
1, record 2, English, Rev%20Responsive%20Element
correct
Record 2, Abbreviations, English
- RRE 1, record 2, English, RRE
correct
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
The interaction of the HIV-1 Rev protein with its target, the Rev responsive element (RRE). The Rev regulatory protein of HIV Rev is modular protein with a N-terminal RNA binding motif and near C- terminal activation domain. 1, record 2, English, - Rev%20Responsive%20Element
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- séquence REE
1, record 2, French, s%C3%A9quence%20REE
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Chaque étape du cycle viral peut constituer une cible d’intervention antivirale. Les agent antiviraux en évaluation dans le monde sont :CD4 soluble, anticorps anti-Env intracellulaires ou secrétés, ribozymes, anticorps intracellulaires antiscriptase inverse(anti-RTase) IFN, leurres de séquence TAR, cible de TAT, inhibiteurs transdominants de TAT, leurres de la séquence RRE de réponse à REV, ARN antisens, inhibiteurs transdominants GAG, CD4 intracellulaires, anticorps anti-ENV "suicide-induit". 1, record 2, French, - s%C3%A9quence%20REE
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2010-04-12
Record 3, English
Record 3, Subject field(s)
- Genetics
Record 3, Main entry term, English
- decoy
1, record 3, English, decoy
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
The activity of the HIV-1 regulatory protein, Rev. depends on its binding to the Rev Responsive Element (RRE), located within viral mRNAs encoding key structural and regulatory proteins. ... The Rev system's essential nature and treshold characteristics make it attractive target for a genetic anti-viral strategy .... To pursue this strategy, we have constructed AAV as in different combinations. These include anti-Rev single chain antibodies (anti-Rev SFV), an optimized RRE decoy, and RRE antisense oligonucleotide gene cassettes. 1, record 3, English, - decoy
Record 3, French
Record 3, Domaine(s)
- Génétique
Record 3, Main entry term, French
- leurre
1, record 3, French, leurre
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Chaque étape du cycle viral peut constituer une cible d’intervention antivirale. Les agents antiviraux en évaluation dans le monde sont :CD4 soluble, anticorps anti-Env intracellulaires ou secrétés, ribozymes, anticorps intracellulaires antiscriptase inverse(anti-RTase) IFN, leurres de séquence TAR, cible de TAT, inhibiteurs transdominants de TAT, leurres de la séquence RRE de réponse à REV, ARN antisens, inhibiteurs transdominants GAG, CD4 intracellulaires, anticorps anti-ENV "suicide-induit". 1, record 3, French, - leurre
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2005-02-21
Record 4, English
Record 4, Subject field(s)
- Microbiology and Parasitology
- Biochemistry
Record 4, Main entry term, English
- recombinant soluble CD4
1, record 4, English, recombinant%20soluble%20CD4
correct
Record 4, Abbreviations, English
- rCD4 1, record 4, English, rCD4
correct
- rsCD4 1, record 4, English, rsCD4
correct
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
Recombinant soluble CD4 (rsCD4, rCD4): rCD4 is a soluble form of the CD4 receptors attached to the surface of T4 cells. rCd4 is produced by recombinant DNA biotechnology using mammalian and insect cell lines. HIV binds to CD4 in order to gain entry into the cells. The hope is that rsCd4 when given to patients, will bind to the virus and neutralize it. 1, record 4, English, - recombinant%20soluble%20CD4
Record 4, French
Record 4, Domaine(s)
- Microbiologie et parasitologie
- Biochimie
Record 4, Main entry term, French
- CD4 soluble recombinée
1, record 4, French, CD4%20soluble%20recombin%C3%A9e
correct, feminine noun
Record 4, Abbreviations, French
- rCD4 2, record 4, French, rCD4
feminine noun
Record 4, Synonyms, French
- CD4 soluble recombinée 1, record 4, French, CD4%20soluble%20%20recombin%C3%A9e
correct, feminine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 OBS
La protéine CD4 soluble, synthétisée par génie génétique, pourrait servir de leurre-chélateur du V. I. H. Elle se fixerait sur la gp120 du V. I. H., empêchant sa liaison sur le récepteur membranaire des lymphocytes T4. De nombreuses formes de CD4 solubles ont été obtenues par la technologie de l'ADN recombinant(rCD4). Ces rCD4 inhibent l'infection par le VIH, ainsi que la réplication de la fusion cellulaire induite par le VIH.(D'après les sources c et d). 1, record 4, French, - CD4%20soluble%20recombin%C3%A9e
Record number: 4, Textual support number: 2 OBS
Recombinant ou mieux encore recombiné: qui est synthétisé par génie génétique. 1, record 4, French, - CD4%20soluble%20recombin%C3%A9e
Record 4, Key term(s)
- CD4 soluble recombinante
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Microbiología y parasitología
- Bioquímica
Record 4, Main entry term, Spanish
- CD4 soluble recombinante
1, record 4, Spanish, CD4%20soluble%20recombinante
feminine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2001-09-14
Record 5, English
Record 5, Subject field(s)
- Genetics
- Human Diseases
Record 5, Main entry term, English
- soluble CD4
1, record 5, English, soluble%20CD4
correct
Record 5, Abbreviations, English
- sCD4 1, record 5, English, sCD4
correct
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
A soluble form of the CD4 receptor can either enhance or inhibit the infection of cells by simian immunodeficiency virus (SIV) and human immunodeficiency virus. 1, record 5, English, - soluble%20CD4
Record 5, French
Record 5, Domaine(s)
- Génétique
- Maladies humaines
Record 5, Main entry term, French
- CD4 soluble
1, record 5, French, CD4%20soluble
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Principales stratégies de thérapie génique de l'infection par le VIH :CD4 soluble bloquant la fixation des particules sur le récepteur CD4 [...]. 2, record 5, French, - CD4%20soluble
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 1993-03-21
Record 6, English
Record 6, Subject field(s)
- Immunology
Record 6, Main entry term, English
- CD4 marker 1, record 6, English, CD4%20marker
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
CD markers: New designation for human lymphocyte surface protein recognized by antibodies. Some are identical to OKT antigens. ... T4 (CD4), present on helper cells, is involved in MHC class 2 restricted interactions. 1, record 6, English, - CD4%20marker
Record number: 6, Textual support number: 1 OBS
Formerly designated T4. 1, record 6, English, - CD4%20marker
Record 6, French
Record 6, Domaine(s)
- Immunologie
Record 6, Main entry term, French
- oritéube CD4
1, record 6, French, orit%C3%A9ube%20CD4
masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
- molécule CD4 2, record 6, French, mol%C3%A9cule%20CD4
feminine noun
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
La protéine CD4 a-t-elle un avenir dans le traitement du SIDA? Le marqueur de membrane CD4, caractéristique de certaines sous-populations de lymphocyte T(cellules accessoires ou helper) est le récepteur principal des virus du SIDA HIV-1 ET hiv-2; il se fixe spécifiquement à la glycoprotéine de surface gp 120 de ces virus. [...] cette molécule, sous une forme soluble, pourrait se lier aux virus et inhiber leur fixation au récepteur CD4 des cellules T, bloquant ainsi leur infectiosité. 1, record 6, French, - orit%C3%A9ube%20CD4
Record number: 6, Textual support number: 2 CONT
(Les virus HIV) pénètrent les cellules qui portent un récepteur spécifique à leur surface (la molécule CDA présente sur la surface des lymphocytes T auxiliaires et probablement des neurones). 2, record 6, French, - orit%C3%A9ube%20CD4
Record 6, Spanish
Record 6, Textual support, Spanish
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