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CYTOTOXICITE MEDIATION LYMPHOCYTAIRE [1 record]
Record 1 - internal organization data 1993-03-05
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- cell-mediated lympholysis 1, record 1, English, cell%2Dmediated%20lympholysis
Record 1, Abbreviations, English
Record 1, Synonyms, English
- lymphocyte-mediated cytotoxicity 2, record 1, English, lymphocyte%2Dmediated%20cytotoxicity
- CTL-mediated lysis 2, record 1, English, CTL%2Dmediated%20lysis
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A variation of the mixed lymphocyte culture (MLC) techniques that is a functional test of the ability of cytotoxic lymphocytes (CTL) to kill target cells. Lymphocytes from two individuals are cultured together for several days, one population having been prevented from proliferating by treatment with radiation or mitomycin (a "one-way" MLC); they are then cultured for several hours with 51CR-labeled target cells that are HLA-identical to the stimulator cells. Cytotoxicity is measured as percentage of 51CR released from specific target cells compared to percentage of 51CR released from control (nonspecific target) cells. 1, record 1, English, - cell%2Dmediated%20lympholysis
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- cytotoxicité à médiation lymphocytaire
1, record 1, French, cytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20lymphocytaire
feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- lymphocytotoxicité à médiation cellulaire 2, record 1, French, lymphocytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20cellulaire
feminine noun
- lympholyse à médiation cellulaire 3, record 1, French, lympholyse%20%C3%A0%20m%C3%A9diation%20cellulaire
feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Test de cytotoxicité à médiation lymphocytaire. Lorsque des lymphocytes provenant de deux populations allogéniques différentes sont mis en présence dans un tube, on assiste à l'apparition de lymphoblastes(ce qui définit la réaction lymphocytaire mixte), mais aussi à celle d’une génération de cellules T cytotoxiques spécifiques. C'est la réaction de lymphocytotoxicité à médiation cellulaire appelée en anglais "cell mediated lympholysis". 1, record 1, French, - cytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20lymphocytaire
Record 1, Spanish
Record 1, Textual support, Spanish
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