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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Sickle cell retinopathy is present in some patients with sickle cell disease. In sickle cell retinopathy, blockage of blood vessels in the retina and choroid ... results in abnormal blood vessel growth and thinning of the retina. ... Sickle cell maculopathy, which affects the center part of the retina, occurs when there is decreased blood flow to this part of the eye. This abnormal blood flow causes patches of retinal thinning ... Patients will sometimes note blind spots as a result.  3, record 1, English, - sickle%20cell%20maculopathy

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

La drépanocytose est une maladie systémique hématologique induisant la survenue d’événements vaso-occlusifs de divers organes cibles. Sur le plan oculaire, l'atteinte rétinienne se caractérise par des occlusions préférentiellement artérielles et de la vascularisation terminale, pouvant se compliquer de néovascularisation périphérique. Longtemps ignorée, la maculopathie drépanocytaire est désormais bien caractérisée grâce à l'imagerie multimodale[. Une] étude de cas suggère que la maculopathie drépanocytaire, caractérisée par des amincissements rétiniens focaux, proviendrait d’une ischémie du plexus capillaire rétinien profond, à l'origine d’une atrophie tissulaire séquellaire.  2, record 1, French, - maculopathie%20dr%C3%A9panocytaire

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

Any of the diseases associated with the presence of hemoglobin S and sickle cells ...  7, record 2, English, - sickle%20cell%20disease

Record number: 2, Textual support number: 1 OBS

[It includes] sickle cell anemia, sickle cell-hemoglobin C disease, sickle cell-hemoglobin D disease, and sickle cell-thalassemia disease.  7, record 2, English, - sickle%20cell%20disease

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Les altérations cellulaires sont une constante de la maladie drépanocytaire. En effet, dans sa forme désoxygénée l’HbS [hémoglobine S] polymérise et déforme le globule rouge qui devient fragile et rigide. Ce dernier prend alors la forme d’une faucille d’où le nom de falciformation donné à ce phénomène.  5, record 2, French, - maladie%20falciforme

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

Sickle cell anemia is an inherited disorder of the globin chains that causes hemolysis and chronic organ damage. Sickle cell anemia is the most common form of sickle cell disease (SCD), with a lifelong affliction of hemolytic anemia requiring blood transfusions, pain crises, and organ damage.  5, record 3, English, - sickle%20cell%20anemia

Record number: 3, Textual support number: 1 OBS

... sickle cell anaemia is the main form of SCD [sickle cell disease], in which the person inherits the gene encoding sickle haemoglobin (HbS) from both biological parents.  6, record 3, English, - sickle%20cell%20anemia

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Pour qu’un enfant soit atteint d’anémie à hématies falciformes, il faut que ses deux parents lui aient transmis le gène de l’hémoglobine S. Si un seul parent lui transmet le gène, l’enfant sera lui aussi porteur du gène fautif, mais il ne souffrira pas de cette maladie.  1, record 3, French, - an%C3%A9mie%20%C3%A0%20h%C3%A9maties%20falciformes

Record number: 3, Textual support number: 1 OBS

drépanocytose : Bien que la désignation «drépanocytose» désigne l'ensemble des maladies causées par la présence d’hémoglobine S, certains auteurs l'utilisent comme synonyme de la désignation «anémie à hématies falciformes» qui correspond à la forme homozygote de la maladie falciforme.  6, record 3, French, - an%C3%A9mie%20%C3%A0%20h%C3%A9maties%20falciformes

Record 3,  Textual support,  Spanish

Record number: 3, Textual support number: 1 CONT

La anemia falciforme es una anemia hemolítica severa con alto índice de mortalidad y es hereditaria con patrón de herencia autosómica recesiva.  1, record 3, Spanish, - anemia%20falciforme

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 OBS

The Sickle Cell Foundation of Alberta (SCFA) is a volunteer-based organization dedicated to creating awareness about SCD [sickle cell disease] and providing support services to patients living in Alberta ... The SCFA teaches patients coping skills for pain management, advocates for funding of SCD research and provides its members with access to the most current scientific research and information.  2, record 4, English, - Sickle%20Cell%20Foundation%20of%20Alberta

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 OBS

Organisme bénévole voué à la sensibilisation à la drépanocytose, [la] Sickle Cell Foundation of Alberta(SCFA) se consacre à offrir des services de soutien aux patients vivant en Alberta. [Les] patients atteints de drépanocytose [se font enseigner] les habiletés d’adaptation leur permettant de faire face à leur douleur […]  1, record 4, French, - Sickle%20Cell%20Foundation%20of%20Alberta

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

A vertebra characterized by the abrupt indentation of the vertebral endplates. It is a relatively specific roentgenographic sign of anemia but has been described in other conditions, including thalassemia, Gaucher's disease, congenital hereditary spherocytosis, and osteoporosis.  2, record 5, English, - H%20vertebra

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

La vertèbre en H par tassement médian à bords abrupts des plateaux vertébraux s’observe non seulement dans la drépanocytose, mais aussi dans la maladie de Gaucher.  1, record 5, French, - vert%C3%A8bre%20en%20H

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

Unusually late sexual maturity.  2, record 6, English, - delayed%20puberty

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Puberté tardive. Développement de la puberté retardée. Certains enfants atteints de drépanocytose grandissent moins vite que d’autres. Cela signifie que durant toute leur enfance, ils sont plus petits et plus minces que les enfants de leur âge. Le début de la puberté est également souvent retardé, quelque fois de plusieurs années. [...] En général, les filles [...] ont terminé leur croissance à seize ans et les garçons à dix-huit ans.  3, record 6, French, - pubert%C3%A9%20tardive

Record 6,  Textual support,  Spanish

Record number: 6, Textual support number: 1 DEF

Aparición de caracteres sexuales secundarios después de: 14 años en el varón, 13 años en la mujer o si transcurrieron más de 5 años entre la primera evidencia de pubertad y el desarrollo genital completo en el varón y la menarquia en la mujer.  2, record 6, Spanish, - pubertad%20tard%C3%ADa

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

An erythrocyte shaped like a sickle or crescent, the abnormal shape caused by the presence of varying proportions of hemoglobin S.  1, record 7, English, - sickle%20cell

Record number: 7, Textual support number: 1 OBS

When a person with sickle cell anemia is exposed to dehydration, infection, or low oxygen supply, their fragile red blood cells form liquid crystals and assume a crescent shape causing red cell destruction and thickening of the blood.  1, record 7, English, - sickle%20cell

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

La drépanocytose [...] la polymérisation de l'Hb [l'hémoglobine] en de longues fibres [déforme le globule rouge] en lui donnant l'aspect d’une faucille(drépanocyte).  2, record 7, French, - dr%C3%A9panocyte

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 DEF

Hematíe maduro en forma de hoz, debido a la presencia de una hemoglobina anormal.  2, record 7, Spanish, - drepanocito

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 OBS

Said of a type of anemia  2, record 8, English, - drepanocytic

Record number: 8, Textual support number: 1 CONT

Sickel cell disease (drepanocytic anemia) is an hemolytic anemia with RBC assuming characteristic sickle cell shape (drepanocytes) due to abnormal B globin subunit (substitution of valine for glutamic acid at the 6th position from the N-terminus). Roughly 8% of American blacks are heterozygous for the trait.  3, record 8, English, - drepanocytic

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 DEF

Se dit d’une personne atteinte d’anémie falciforme(ou drépanocytose).  1, record 8, French, - dr%C3%A9panocytaire

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 DEF

A condition marked by the presence of numbers of schistocytes in the blood.  1, record 9, English, - schistocytosis

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 DEF

Présence de schizocytes dans le sang.  2, record 9, French, - schizocytose

Record number: 9, Textual support number: 1 CONT

Hémogramme [...] Globules rouges. L'examen au microscope permet de reconnaître des anomalies :-de taille : macrocytose, microcytose, anisocytose-de forme : schizocytose, drépanocytose, etc...  1, record 9, French, - schizocytose

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 DEF

An angled deformity of the tibiotalar joint due to asymmetrical growth of the distal tibial epiphysis. The medial aspect of the joint may be a half inch lower than the lateral articulating margin. Seen in hemophilia, juvenile rheumatoid arthritis, sickle-cell anemia, fracture, and multiple epiphyseal dysplasia. [From GBONE, 1980, p. 91 and EBONE, 1981, pp. 591, 601.]  2, record 10, English, - tibiotalar%20slant

Record number: 10, Textual support number: 1 OBS

The tibiotalar slant may be a positioning artifact, caused by external rotation and elevation of the proximal tibia, if the central ray of the x-ray beam is not perpendicular.  3, record 10, English, - tibiotalar%20slant

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 DEF

Déformation en pente de l'articulation tibio-tarsienne liée à la croissance anormale de l'épiphyse tibiale. La surface interne de l'articulation se trouve plus basse que la surface articulaire externe. Les causes les plus fréquentes : hémophilie, arthrite chronique juvénile, drépanocytose, fracture et dysplasie polyépiphysaire.  2, record 10, French, - bascule%20de%20l%26rsquo%3Barticulation%20tibio%2Dtarsienne

Record number: 10, Textual support number: 1 OBS

À ne pas confondre avec un artefact résultant de la rotation externe et de l’élévation de la partie supérieure du tibia lorsque le rayon directeur n’est pas perpendiculaire au plan articulaire.  2, record 10, French, - bascule%20de%20l%26rsquo%3Barticulation%20tibio%2Dtarsienne

Record number: 10, Textual support number: 2 OBS

source d : EMSQU, 1990, A10, 31191, p. 3.  2, record 10, French, - bascule%20de%20l%26rsquo%3Barticulation%20tibio%2Dtarsienne

Record 10,  Textual support,  Spanish