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DRUSEN [3 records]
Record 1 - internal organization data 2025-09-11
Record 1, English
Record 1, Subject field(s)
- Visual Disorders
Record 1, Main entry term, English
- Sorsby's macular dystrophy
1, record 1, English, Sorsby%27s%20macular%20dystrophy
correct, noun
Record 1, Abbreviations, English
Record 1, Synonyms, English
- Sorsby's fundus dystrophy 2, record 1, English, Sorsby%27s%20fundus%20dystrophy
correct, noun
- Sorsby's dystrophy 3, record 1, English, Sorsby%27s%20dystrophy
correct, noun
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Sorsby's macular dystrophy. ... This is an extremely rare, dominantly inherited disorder, with many clinical similarities to age-related macular degeneration. A gene for Sorsby's dystrophy that codes for a tissue inhibitor metalloproteinase, TIMP-3, has been identified. ... Several mutations of TIMP-3 have been identified in patients with Sorsby's dystrophy. ... Early in the disease process, several very fine drusen or a large confluent plaque or yellowish material may be noted beneath the central RPE [retinal pigment epithelium]. Then, typically around 40 years of age, patients develop bilateral exudative maculopathy, which leaves heavily pigmented macular scars and areas of geographical atrophy. 4, record 1, English, - Sorsby%27s%20macular%20dystrophy
Record 1, Key term(s)
- Sorsby macular dystrophy
- Sorsby fundus dystrophy
- Sorsby dystrophy
Record 1, French
Record 1, Domaine(s)
- Troubles de la vision
Record 1, Main entry term, French
- dystrophie maculaire de Sorsby
1, record 1, French, dystrophie%20maculaire%20de%20Sorsby
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- dystrophie de Sorsby 2, record 1, French, dystrophie%20de%20Sorsby
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La dystrophie de Sorsby est une dystrophie maculaire de transmission autosomique dominante liée à une mutation sur le gène TIMP3. Le phénotype est caractérisé par l'apparition de drusen et de néovaisseaux et une atrophie rétinienne survenant entre la 3e et 6e décennie. La pathologie est progressive et cécitante. 3, record 1, French, - dystrophie%20maculaire%20de%20Sorsby
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2025-06-20
Record 2, English
Record 2, Subject field(s)
- Visual Disorders
Record 2, Main entry term, English
- dry age-related macular degeneration
1, record 2, English, dry%20age%2Drelated%20macular%20degeneration
correct, noun
Record 2, Abbreviations, English
Record 2, Synonyms, English
- atrophic age-related macular degeneration 2, record 2, English, atrophic%20age%2Drelated%20macular%20degeneration
correct, noun
- non-exudative age-related macular degeneration 3, record 2, English, non%2Dexudative%20age%2Drelated%20macular%20degeneration
correct, noun
- non-neovascular age-related macular degeneration 4, record 2, English, non%2Dneovascular%20age%2Drelated%20macular%20degeneration
correct, noun
- dry AMD 5, record 2, English, dry%20AMD
correct, noun
- atrophic AMD 2, record 2, English, atrophic%20AMD
correct, noun
- non-exudative AMD 3, record 2, English, non%2Dexudative%20AMD
correct, noun
- non-neovascular AMD 4, record 2, English, non%2Dneovascular%20AMD
correct, noun
- dry ARMD 6, record 2, English, dry%20ARMD
correct, noun
- atrophic ARMD 7, record 2, English, atrophic%20ARMD
correct, noun
- non-exudative ARMD 8, record 2, English, non%2Dexudative%20ARMD
correct, noun
- non-neovascular ARMD 9, record 2, English, non%2Dneovascular%20ARMD
correct, noun
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Dry age-related macular degeneration. This form is quite common. About 80 percent ... of people who have AMD [age-related macular degeneration] have the dry form. Dry AMD is when parts of the macula get thinner with age and tiny clumps of protein called drusen grow. People with dry AMD may have drusen, pigment abnormalities, or geographic atrophy (an area of cell loss in the retina). You slowly lose central vision. 10, record 2, English, - dry%20age%2Drelated%20macular%20degeneration
Record 2, Key term(s)
- nonexudative age-related macular degeneration
- nonexudative AMD
- nonexudative ARMD
Record 2, French
Record 2, Domaine(s)
- Troubles de la vision
Record 2, Main entry term, French
- dégénérescence maculaire sèche liée à l’âge
1, record 2, French, d%C3%A9g%C3%A9n%C3%A9rescence%20maculaire%20s%C3%A8che%20li%C3%A9e%20%C3%A0%20l%26rsquo%3B%C3%A2ge
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- dégénérescence maculaire atrophique liée à l’âge 2, record 2, French, d%C3%A9g%C3%A9n%C3%A9rescence%20maculaire%20atrophique%20li%C3%A9e%20%C3%A0%20l%26rsquo%3B%C3%A2ge
correct, feminine noun
- DMLA sèche 3, record 2, French, DMLA%20s%C3%A8che
correct, feminine noun
- DMLA atrophique 4, record 2, French, DMLA%20atrophique
correct, feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Il existe deux formes de DMLA [dégénérescence maculaire liée à l'âge]. La DMLA sèche est la plus courante. Elle est causée par le vieillissement et la détérioration des mécanismes qui «nettoient» la macula. Les déchets provenant de la destruction de cellules forment alors des dépôts jaunâtres, appelés «druses» ou «drusen», qui s’accumulent sous la rétine. À un stade tardif, ils provoquent la mort des cellules de la macula qui captent la lumière(cellules photoréceptrices), ce qui altère la vision centrale. La forme sèche évolue généralement lentement. 5, record 2, French, - d%C3%A9g%C3%A9n%C3%A9rescence%20maculaire%20s%C3%A8che%20li%C3%A9e%20%C3%A0%20l%26rsquo%3B%C3%A2ge
Record number: 2, Textual support number: 1 OBS
DMLA : dégénérescence maculaire liée à l’âge. 6, record 2, French, - d%C3%A9g%C3%A9n%C3%A9rescence%20maculaire%20s%C3%A8che%20li%C3%A9e%20%C3%A0%20l%26rsquo%3B%C3%A2ge
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 1990-02-05
Record 3, English
Record 3, Subject field(s)
- Symptoms (Medicine)
- Visual Disorders
- Musculoskeletal System
Record 3, Main entry term, English
- drüsen
1, record 3, English, dr%C3%BCsen
correct, plural
Record 3, Abbreviations, English
Record 3, Synonyms, English
- drüsen bodies 2, record 3, English, dr%C3%BCsen%20bodies
correct, plural
- colloid bodies 3, record 3, English, colloid%20bodies
correct, plural
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
Small, discrete, yellowish-white spots seen scattered over the fundus of the eye, consisting of hyaline material situated in Bruch's membrane. They are found usually as a degenerative change in old age and following disease of the retina. 4, record 3, English, - dr%C3%BCsen
Record number: 3, Textual support number: 1 OBS
Can be seen in pseudoxanthoma elasticum. 5, record 3, English, - dr%C3%BCsen
Record number: 3, Textual support number: 2 OBS
The term "drusen" is recommended by the Medical Signs and Symptoms Committee. 6, record 3, English, - dr%C3%BCsen
Record 3, French
Record 3, Domaine(s)
- Symptômes (Médecine)
- Troubles de la vision
- Appareil locomoteur (Médecine)
Record 3, Main entry term, French
- drusen
1, record 3, French, drusen
correct
Record 3, Abbreviations, French
Record 3, Synonyms, French
- corps colloïdes 2, record 3, French, corps%20collo%C3%AFdes
correct, masculine noun, plural
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Petites formations perlées, blanc jaunâtre, électivement localisées soit sur la papille [...] soit sur la lame vitrée de la membrane de Bruch [...] et considérées comme une manifestation sénile ou de dégénérescence secondaire. 1, record 3, French, - drusen
Record number: 3, Textual support number: 1 OBS
Peut s’observer dans le pseudo-xanthome élastique. 3, record 3, French, - drusen
Record number: 3, Textual support number: 2 OBS
Le terme «drusen» a été retenu par le Comité de sémiologie médicale. 4, record 3, French, - drusen
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Síntomas (Medicina)
- Trastornos de la visión
- Sistema musculoesquelético (Medicina)
Record 3, Main entry term, Spanish
- drusas
1, record 3, Spanish, drusas
feminine noun, plural
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
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