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DYSTROGLYCANE [1 record]

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Record 1 2011-12-12

English

Subject field(s)
  • Biochemistry
  • Molecular Biology
DEF

A molecule part of the dystrophin-associated protein complex that participates in the formation of the extracellular matrix in cells contacting basement membranes.

French

Domaine(s)
  • Biochimie
  • Biologie moléculaire
CONT

Du côté aminoterminal, la dystrophine se fixe aux filaments d’actine γ du cytosquelette, du coté carboxyterminal, elle s’attache à un complexe de glycoprotéines transmembranaires, les dystroglycanes. Ceux-ci interagissent avec un autre complexe transmembranaire, les sarcoglycanes, et avec la laminine qui s’attache au collagène extracellulaire [...], établissant une continuité mécanique entre le cytosquelette et la matrice extracellulaire.

Spanish

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