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DYSTROPHIE MACULAIRE STARGARDT [2 records]
Record 1 - internal organization data 2026-03-25
Record 1, English
Record 1, Subject field(s)
- Eye Surgery
Record 1, Main entry term, English
- retinal pigmented epithelium transplantation
1, record 1, English, retinal%20pigmented%20epithelium%20transplantation
correct, noun
Record 1, Abbreviations, English
Record 1, Synonyms, English
- retinal pigment epithelium transplantation 2, record 1, English, retinal%20pigment%20epithelium%20transplantation
correct, noun
- RPE transplantation 3, record 1, English, RPE%20transplantation
correct, noun
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Replacement of the retinal pigment epithelium (RPE) is emerging as a promising approach to treat degenerative retinal diseases, including age-related macular degeneration and Stargardt disease, in which RPE function cannot otherwise be restored. Despite the limitations of existing treatments, advances in cell sourcing and surgical methods have enabled initial human trials of RPE transplantation, with early results indicating potential efficacy. 4, record 1, English, - retinal%20pigmented%20epithelium%20transplantation
Record 1, French
Record 1, Domaine(s)
- Chirurgie de l'œil
Record 1, Main entry term, French
- greffe d’épithélium pigmentaire rétinien
1, record 1, French, greffe%20d%26rsquo%3B%C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Neuf patients âgés de 55 ans et plus ont reçu une greffe d’épithélium pigmentaire rétinien. Vingt-deux mois après la greffe, aucun signe de prolifération anormale, de rejet ou d’affection oculaire ou systémique n’a pu être décelé. Une amélioration de l’acuité visuelle globale a été observée. 2, record 1, French, - greffe%20d%26rsquo%3B%C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien
Record number: 1, Textual support number: 1 OBS
Chirurgie effectuée dans le cadre d’un traitement de la dégénérescence maculaire liée à l'âge ou une dystrophie maculaire de Stargardt. 3, record 1, French, - greffe%20d%26rsquo%3B%C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2025-08-27
Record 2, English
Record 2, Subject field(s)
- Visual Disorders
Record 2, Main entry term, English
- Stargardt's disease
1, record 2, English, Stargardt%27s%20disease
correct, noun
Record 2, Abbreviations, English
Record 2, Synonyms, English
- Stargardt disease 2, record 2, English, Stargardt%20disease
correct, noun
- Stargardt's macular dystrophy 3, record 2, English, Stargardt%27s%20macular%20dystrophy
correct, noun
- Stargardt macular dystrophy 4, record 2, English, Stargardt%20macular%20dystrophy
correct, noun
- Stargardt's macular degeneration 5, record 2, English, Stargardt%27s%20macular%20degeneration
noun
- Stargardt macular degeneration 6, record 2, English, Stargardt%20macular%20degeneration
noun
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Stargardt's disease is the most common cause of juvenile macular dystrophy that can cause progressive central visual loss. ... The disease affects the retinal pigment epithelium (RPE) and photoreceptor layers, and typically has an onset in childhood or young adulthood. The disease is caused by mutations in gene encoding photoreceptor cell-specific-ATP-binding cassette transporter ABCA4 that leads to an abnormal accumulation of lipofuscin in the RPE and the photoreceptors causing degenerative changes. 7, record 2, English, - Stargardt%27s%20disease
Record 2, French
Record 2, Domaine(s)
- Troubles de la vision
Record 2, Main entry term, French
- maladie de Stargardt
1, record 2, French, maladie%20de%20Stargardt
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- dystrophie maculaire de Stargardt 2, record 2, French, dystrophie%20maculaire%20de%20Stargardt
correct, feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
La maladie de Stargardt est la forme la plus fréquente de dystrophie maculaire juvénile à transmission autosomique récessive caractérisée par l'existence d’une lésion maculaire bilatérale ayant un aspect en œil de bœuf en rapport avec l'accumulation de pigment lipofuscine au niveau l'épithélium pigmentaire. 3, record 2, French, - maladie%20de%20Stargardt
Record 2, Spanish
Record 2, Textual support, Spanish
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