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EPISSAGE ALTERNATIF [2 records]
Record 1 - internal organization data 2022-01-04
Record 1, English
Record 1, Subject field(s)
- Genetics
- Molecular Biology
Record 1, Main entry term, English
- splice variant
1, record 1, English, splice%20variant
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Alternative splicing is a highly regulated process with the potential to express a splice variant only under specific spatio-temporal conditions. 2, record 1, English, - splice%20variant
Record number: 1, Textual support number: 2 CONT
Splice variants play an important role within the cell in both increasing the proteome diversity and in cellular function. Splice variants are also associated with disease states and may play a role in their etiology. 3, record 1, English, - splice%20variant
Record 1, French
Record 1, Domaine(s)
- Génétique
- Biologie moléculaire
Record 1, Main entry term, French
- variant d’épissage
1, record 1, French, variant%20d%26rsquo%3B%C3%A9pissage
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Grâce à [l'épissage alternatif], plusieurs ARNm [acides ribonucléiques messagers] peuvent être produits à partir d’un même gène. Ces variants d’épissage se distinguent par leur contenu en exons. 2, record 1, French, - variant%20d%26rsquo%3B%C3%A9pissage
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
- Biología molecular
Record 1, Main entry term, Spanish
- variante de empalme
1, record 1, Spanish, variante%20de%20empalme
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
Una variante de empalme del gen producía la proteína AIB1-Delta4, que resultó ser la responsable de promover la comunicación y el reclutamiento de las células circundantes, lo que finalmente conduce a la metástasis. 1, record 1, Spanish, - variante%20de%20empalme
Record 2 - internal organization data 1997-07-10
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- alternative splicing
1, record 2, English, alternative%20splicing
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
The generation of two or more different mature mRNA's from the same primary transcript through variation in the sites of splicing. It is a method of producing structurally and functionally distinct proteins from the same gene and a method of developmental regulation. 1, record 2, English, - alternative%20splicing
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- épissage alternatif
1, record 2, French, %C3%A9pissage%20alternatif
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Expression décrivant la possibilité pour un même ARN pré-messager de subir divers épissages, conduisant à des protéines différentes selon la différenciation de la cellule (ou son état physiologique) où cet épissage est effectué. Les protéines produites à partir d’un même gène présenteront ainsi des domaines protéiques en commun. 2, record 2, French, - %C3%A9pissage%20alternatif
Record number: 2, Textual support number: 1 CONT
[...] un même gène peut coder pour plusieurs protéines. En particulier, le phénomène d’épissage alternatif qui est omniprésent chez tous les eucaryotes pluricellulaires, permet de générer différentes protéines. Dans un cas au moins, il a été montré que l'épissage alternatif conduit à l'expression de protéines complètement distinctes [Alphonso et al. J. Mol. Biol. sous presse, cités dans Fields et al. 1994]. 3, record 2, French, - %C3%A9pissage%20alternatif
Record 2, Spanish
Record 2, Textual support, Spanish
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