TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Replacement of the retinal pigment epithelium (RPE) is emerging as a promising approach to treat degenerative retinal diseases, including age-related macular degeneration and Stargardt disease, in which RPE function cannot otherwise be restored. Despite the limitations of existing treatments, advances in cell sourcing and surgical methods have enabled initial human trials of RPE transplantation, with early results indicating potential efficacy.  4, record 1, English, - retinal%20pigmented%20epithelium%20transplantation

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

Neuf patients âgés de 55 ans et plus ont reçu une greffe d’épithélium pigmentaire rétinien. Vingt-deux mois après la greffe, aucun signe de prolifération anormale, de rejet ou d’affection oculaire ou systémique n’ a pu être décelé. Une amélioration de l'acuité visuelle globale a été observée.  2, record 1, French, - greffe%20d%26rsquo%3B%C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien

Record number: 1, Textual support number: 1 OBS

Chirurgie effectuée dans le cadre d’un traitement de la dégénérescence maculaire liée à l’âge ou une dystrophie maculaire de Stargardt.  3, record 1, French, - greffe%20d%26rsquo%3B%C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

... fundus autofluorescence (FAF) imaging, which detects autofluorescent material, i.e., lipofuscin, in the retinal pigment epithelium (RPE). Fluorophores detectable with this imaging method may also occur anterior or posterior to the RPE cell monolayer. Excessive lipofuscin accumulation in the RPE is a common downstream pathogenic pathway in various monogenetic and complex retinal diseases including age-related macular degeneration. The accumulated lipofuscin produces a signal that is captured in the FAF image allowing in vivo mapping of metabolic changes in the RPE.  6, record 2, English, - fundus%20autofluorescence%20imaging

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 OBS

Technique permettant d’obtenir des images qui révèlent une accumulation de lipofuscine sur l'épithélium pigmentaire rétinien.  4, record 2, French, - imagerie%20en%20autofluorescence%20du%20fond%20d%26rsquo%3B%26oelig%3Bil

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

Central serous retinopathy (CSR) is a pathologic condition characterized by swelling and elevation of retinal tissue near the macula due to accumulation of fluid between the photoreceptor outer segments and the retinal pigment epithelium (RPE), often leading to detachment of the neurosensory retina. Also sometimes called central serous chorioretinopathy, the condition most often affects men 20 to 60 years of age, but it can also affect women. The disease is often unilateral and is self-limiting in about 60% of cases, but sometimes the retinal detachment persists, leading to damage to the RPE and the photoreceptors and resulting in vision loss.  3, record 3, English, - central%20serous%20chorioretinopathy

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

La choriorétinite séreuse centrale(CRSC) est une pathologie idiopathique caractérisée par un décollement séreux localisé de la rétine sensorielle au niveau de la macula secondaire à une fuite de la choriocapillaire à travers l'EPR [épithélium pigmentaire rétinien] par hyperperméabilité. La CRSC survient classiquement chez l'homme jeune ou d’âge moyen.  3, record 3, French, - chorior%C3%A9tinite%20s%C3%A9reuse%20centrale

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

Laser photocoagulation and cryopexy are used to fix tears in the retina and prevent a retinal detachment.  2, record 4, English, - cryopexy

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Cryocoagulation de la rétine, le plus souvent par voie transsclérale pour induire un processus cicatriciel permettant une adhésion solide entre l'épithélium pigmentaire et le neuro-épithélium rétinien.  1, record 4, French, - cryopexie

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

The retinal pigmented epithelium (RPE) is a simple cuboidal epithelium with apical processes which, unlike many epithelia, do not extend freely into a lumen but rather interdigitate closely with the outer segments of the neural retina.  1, record 5, English, - retinal%20pigmented%20epithelium

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Couche brune de la rétine située à côté de la choroïde et composée de cellules remplies de pigments (principalement de lipofuscine et de mélanine).  2, record 5, French, - %C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien

Record number: 5, Textual support number: 1 CONT

[Les] couches [cellulaires], situées au fond de l'œil, correspondent à la choroïde, à l'épithélium pigmentaire rétinien et aux photorécepteurs de la rétine.  3, record 5, French, - %C3%A9pith%C3%A9lium%20pigmentaire%20r%C3%A9tinien

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

[A] sharply delineated round or oval area of hypopigmentation, or apparent absence of the retinal pigment epithelium (RPE), in which choroidal vessels are more visible than in surrounding areas, that must be at least 175 μm in diameter.  2, record 6, English, - geographic%20atrophy

Record number: 6, Textual support number: 1 CONT

Geographic atrophy (GA) is considered the late stage of the dry form of age-related macular degeneration (AMD).  2, record 6, English, - geographic%20atrophy

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

On distingue deux formes cliniques de la DMLA [dégénérescence maculaire liée à l'âge] aux stades tardifs : la forme «sèche» caractérisée par une atrophie géographique de l'EPR [épithélium pigmentaire rétinien] et de la choroïde et la forme «humide» ou exsudative, qui est associée, en plus de l'atrophie, à une néovascularisation choroïdienne(NVC).  2, record 6, French, - atrophie%20g%C3%A9ographique

Record 6,  Textual support,  Spanish