TERMIUM Plus®
From: Translation Bureau
On social media
Consult the Government of Canada’s terminology data bank.
EPITOPE [13 records]
Record 1 - internal organization data 2012-10-16
Record 1, English
Record 1, Subject field(s)
- Bioengineering
- Biotechnology
Record 1, Main entry term, English
- antigenic determinant
1, record 1, English, antigenic%20determinant
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- epitope 1, record 1, English, epitope
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The specific part of an antigen molecule to which an antibody becomes attached. 1, record 1, English, - antigenic%20determinant
Record 1, French
Record 1, Domaine(s)
- Technique biologique
- Biotechnologie
Record 1, Main entry term, French
- déterminant antigénique
1, record 1, French, d%C3%A9terminant%20antig%C3%A9nique
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- épitope 1, record 1, French, %C3%A9pitope
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Surface individuelle caractéristique d’un antigène, qui déclenche la production d’un anticorps spécifique au cours de la réponse immunitaire. 1, record 1, French, - d%C3%A9terminant%20antig%C3%A9nique
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioingeniería
- Biotecnología
Record 1, Main entry term, Spanish
- determinante antigénico
1, record 1, Spanish, determinante%20antig%C3%A9nico
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- epítope 1, record 1, Spanish, ep%C3%ADtope
correct, masculine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Porción específica de un antígeno macromolecular a la que se une un anticuerpo. 2, record 1, Spanish, - determinante%20antig%C3%A9nico
Record number: 1, Textual support number: 1 CONT
Cada determinante antigénico, constituido normalmente por unos pocos aminoácidos, determina la síntesis de un anticuerpo diferente; por tanto, de la exposición a un solo antígeno pueden expresarse varios anticuerpos. 3, record 1, Spanish, - determinante%20antig%C3%A9nico
Record 2 - internal organization data 2011-07-05
Record 2, English
Record 2, Subject field(s)
- Trade Names
- Diagnostic Procedures (Medicine)
Record 2, Main entry term, English
- OraSure®
1, record 2, English, OraSure%C2%AE
correct, trademark
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 OBS
FDA requests more information on OraSure PMA (oral specimen collection device, premarket approval application). Saliva-based AIDS test studied for insurance industry. 2, record 2, English, - OraSure%C2%AE
Record number: 2, Textual support number: 2 OBS
Term and context extracted from the data base. 2, record 2, English, - OraSure%C2%AE
Record number: 2, Textual support number: 3 OBS
A trademark of Epitope Inc.'s OraSure. 2, record 2, English, - OraSure%C2%AE
Record 2, Key term(s)
- OraSure
Record 2, French
Record 2, Domaine(s)
- Appellations commerciales
- Méthodes diagnostiques (Médecine)
Record 2, Main entry term, French
- OraSure®
1, record 2, French, OraSure%C2%AE
correct, trademark
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 OBS
Marque de commerce de Epitope Inc. 's OraSure. 1, record 2, French, - OraSure%C2%AE
Record 2, Key term(s)
- OraSure
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2007-08-14
Record 3, English
Record 3, Subject field(s)
- Immunology
Record 3, Main entry term, English
- epitope vaccine
1, record 3, English, epitope%20vaccine
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
- epitope-based vaccine 2, record 3, English, epitope%2Dbased%20vaccine
correct
- epitope-driven vaccine 2, record 3, English, epitope%2Ddriven%20vaccine
correct
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
The epitope-driven vaccine concept is an attractive one that is being successfully pursued in a number of laboratories ... A typical epitope-based vaccine construct contains a single start codon with coding sequences for epitopes inserted consecutively in the construct, with or without intervening spacer amino acids. 2, record 3, English, - epitope%20vaccine
Record 3, Key term(s)
- epitope based vaccine
- epitope driven vaccine
Record 3, French
Record 3, Domaine(s)
- Immunologie
Record 3, Main entry term, French
- vaccin épitopique
1, record 3, French, vaccin%20%C3%A9pitopique
masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
La réaction de défense des lymphocytes de l'organisme ne se fait pas sur des protéines entières mais sur des fragments d’acide aminés qui la composent et que l'on appelle des épitopes [...] le vaccin épitopique protège contre l'épitope en question et que contre celui-ci [...] 1, record 3, French, - vaccin%20%C3%A9pitopique
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2006-05-08
Record 4, English
Record 4, Subject field(s)
- Immunology
Record 4, Main entry term, English
- hole in the repertoire 1, record 4, English, hole%20in%20the%20repertoire
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
... a way of explaining the non-responder status of an animal by saying that it lacks some particular antigen receptor. 1, record 4, English, - hole%20in%20the%20repertoire
Record 4, French
Record 4, Domaine(s)
- Immunologie
Record 4, Main entry term, French
- trou dans le répertoire
1, record 4, French, trou%20dans%20le%20r%C3%A9pertoire
masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 DEF
L'une des deux hypothèses contradictoires avancées pour expliquer les mécanismes de l'expression des gènes Ir. [...] le trou dans le répertoire des récepteurs des cellules T par absence de récepteurs capables de reconnaître le complexe formé par l'épitope et l'histotope autologue : absence du gène, délétion clonale ou suppression. 1, record 4, French, - trou%20dans%20le%20r%C3%A9pertoire
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Inmunología
Record 4, Main entry term, Spanish
- hueco en el repertorio
1, record 4, Spanish, hueco%20en%20el%20repertorio
correct, masculine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2006-05-05
Record 5, English
Record 5, Subject field(s)
- Immunology
Record 5, Main entry term, English
- internal image of the antigen 1, record 5, English, internal%20image%20of%20the%20antigen
Record 5, Abbreviations, English
Record 5, Synonyms, English
- internal image anti-idiotype 1, record 5, English, internal%20image%20anti%2Didiotype
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
Internal image anti-idiotype. If a site associated anti-idiotype binds to the paratope of the idiotype in the same way that the antigen does, then the antigen and the anti-idiotype may have the same shape. In this case the anti-idiotype is said to be an internal image of the antigen - internal because it is generated by the immune system itself as opposed to the foreign antigen which is external 1, record 5, English, - internal%20image%20of%20the%20antigen
Record 5, French
Record 5, Domaine(s)
- Immunologie
Record 5, Main entry term, French
- image interne de l’antigène
1, record 5, French, image%20interne%20de%20l%26rsquo%3Bantig%C3%A8ne
feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
- image interne de l'épitope 1, record 5, French, image%20interne%20de%20l%27%C3%A9pitope
feminine noun
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Le réseau idiotypique.-[...] Le postulat primordial qui a été proposé par Niels Jerne est que le paratope d’un anticorps(son site de reconnaissance) est capable de reconnaître un épitope externe(un antigène étranger) mais aussi un idiotope d’un autre anticorps. On dit que cet idiotope est l'image interne de l'épitope, ce qui signifie que les déterminants des sites de reconnaissance des anticorps d’une personne sont équivalents au monde des déterminants antigéniques extérieurs. Figure 1. Le réseau idiotypique «classique», AB-2=image interne de l'antigène. AB-1=AB-3=AB’-1. 1, record 5, French, - image%20interne%20de%20l%26rsquo%3Bantig%C3%A8ne
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Inmunología
Record 5, Main entry term, Spanish
- antiidiotipo de imagen interna
1, record 5, Spanish, antiidiotipo%20de%20imagen%20interna
correct, masculine noun
Record 5, Abbreviations, Spanish
Record 5, Synonyms, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2006-05-05
Record 6, English
Record 6, Subject field(s)
- Immunology
Record 6, Main entry term, English
- histotope 1, record 6, English, histotope
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 DEF
This is the part of the MHC molecule which is recognized by the T cell. 1, record 6, English, - histotope
Record 6, French
Record 6, Domaine(s)
- Immunologie
Record 6, Main entry term, French
- histotope
1, record 6, French, histotope
masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
[...] les animaux NR ne répondent pas à l'antigène parce que leurs cellules sont incapables de reconnaître le complexe formé par la molécule d’antigène(ou épitope) avec la molécule d’antigène de classe II autologue(ou histotope). 1, record 6, French, - histotope
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Inmunología
Record 6, Main entry term, Spanish
- histotopo
1, record 6, Spanish, histotopo
correct, masculine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2003-07-11
Record 7, English
Record 7, Subject field(s)
- Immunology
Record 7, Main entry term, English
- paratope
1, record 7, English, paratope
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 DEF
The part of an antibody molecule which makes contact with the antigenic determinant (epitope). 2, record 7, English, - paratope
Record 7, French
Record 7, Domaine(s)
- Immunologie
Record 7, Main entry term, French
- paratope
1, record 7, French, paratope
correct, masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
- site anticorps 2, record 7, French, site%20anticorps
masculine noun
- anticorps 3, record 7, French, anticorps
see observation, masculine noun
Record 7, Textual support, French
Record number: 7, Textual support number: 1 CONT
Le site anticorps(appelé paratope) définit l'idiotype de la molécule et reconnaît sur l'antigène un déterminant appelé épitope. Le site anticorps peut lui-même servir d’antigène pour un autre anticorps, les déterminants antigéniques de l'idiotype étant dénommés idiotopes. 4, record 7, French, - paratope
Record number: 7, Textual support number: 1 OBS
Synonyme d’anticorps dans la terminologie de Jerne. 3, record 7, French, - paratope
Record 7, Spanish
Record 7, Campo(s) temático(s)
- Inmunología
Record 7, Main entry term, Spanish
- paratopo
1, record 7, Spanish, paratopo
correct, masculine noun
Record 7, Abbreviations, Spanish
Record 7, Synonyms, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 2003-01-20
Record 8, English
Record 8, Subject field(s)
- Biochemistry
Record 8, Main entry term, English
- immunogenic epitope 1, record 8, English, immunogenic%20epitope
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, French
Record 8, Domaine(s)
- Biochimie
Record 8, Main entry term, French
- épitope immunogénique
1, record 8, French, %C3%A9pitope%20immunog%C3%A9nique
masculine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Bioquímica
Record 8, Main entry term, Spanish
- epitope inmunogénico
1, record 8, Spanish, epitope%20inmunog%C3%A9nico
masculine noun
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
Record 8, Textual support, Spanish
Record 9 - internal organization data 1999-02-05
Record 9, English
Record 9, Subject field(s)
- Biotechnology
Record 9, Main entry term, English
- antiginized antibody
1, record 9, English, antiginized%20antibody
correct
Record 9, Abbreviations, English
Record 9, Synonyms, English
Record 9, Textual support, English
Record number: 9, Textual support number: 1 CONT
We have also licensed technology from Mt. Sinai School of Medicine that involves the use of antigenized or peptidized human immunoglobulins as vaccines and autoimmune modulators. The antigenized antibody system enables the delivery of small peptides to specific cells, and is being used to develop prototype vaccines and a prototype tolerogen for an autoimmune disease. 1, record 9, English, - antiginized%20antibody
Record 9, French
Record 9, Domaine(s)
- Biotechnologie
Record 9, Main entry term, French
- anticorps antigénisé
1, record 9, French, anticorps%20antig%C3%A9nis%C3%A9
correct, masculine noun
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 CONT
Anticorps antigénisé contre le paludisme. [...] La technique consiste à injecter dans la rate(de la souris), un gène recombiné codant une chaîne lourde d’immunoglobuline. Celle-ci est modifiée de manière à présenter, sur la partie impliquée dans la reconnaissance de l'antigène, un épitope de la forme circumporozoïde du Plasmodium falciparum. Dans un premier travail, les scientifiques ont utilisé le gène d’un tel anticorps «antigénisé», exprimant un épitope de P. falciparum reconnu par les lymphocytes B. 1, record 9, French, - anticorps%20antig%C3%A9nis%C3%A9
Record 9, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 1996-06-13
Record 10, English
Record 10, Subject field(s)
- Genetics
Record 10, Main entry term, English
- reverse epitope-tagging 1, record 10, English, reverse%20epitope%2Dtagging
Record 10, Abbreviations, English
Record 10, Synonyms, English
Record 10, Textual support, English
Record number: 10, Textual support number: 1 CONT
Purification of mutant enzymes is a prime requirement of biophysical and biochemical studies. Our investigations on the essential E. Coli enzyme glutaminyl-tRNA sybthetase demand mutant enzymes free of any wild-type protein contamination. However, as it is not possible to express non-complementing mutant enzymes in an E. Coli gInS-deletion strain, we developed a novel strategy to address these problems. Instead of following the common tactic of epitope-tagging the mutant protein of interest on an extrachromosomal genetic element, we fused a reporter epitope to the 5' end of the chromosomal gInS-gene copy: this is referred as reverse epitope-tagging. 1, record 10, English, - reverse%20epitope%2Dtagging
Record 10, French
Record 10, Domaine(s)
- Génétique
Record 10, Main entry term, French
- marquage de l'épitope inverse
1, record 10, French, marquage%20de%20l%27%C3%A9pitope%20inverse
proposal, masculine noun
Record 10, Abbreviations, French
Record 10, Synonyms, French
Record 10, Textual support, French
Record 10, Spanish
Record 10, Textual support, Spanish
Record 11 - internal organization data 1996-06-06
Record 11, English
Record 11, Subject field(s)
- Biotechnology
- Molecular Biology
Record 11, Main entry term, English
- capture antibody
1, record 11, English, capture%20antibody
correct
Record 11, Abbreviations, English
- CAb 2, record 11, English, CAb
correct
Record 11, Synonyms, English
Record 11, Textual support, English
Record number: 11, Textual support number: 1 DEF
An antibody that is immobilized on solid matrix and that is able to bind selectively to a target antigen, thereby removing it from a sample. 1, record 11, English, - capture%20antibody
Record 11, French
Record 11, Domaine(s)
- Biotechnologie
- Biologie moléculaire
Record 11, Main entry term, French
- anticorps de capture
1, record 11, French, anticorps%20de%20capture
correct, masculine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
Record 11, Textual support, French
Record number: 11, Textual support number: 1 CONT
À partir d’un ensemble d’anticorps monoclonaux de souris réagissant avec un épitope répété de l'antigène anodique circulant des schistosomes, on a sélectionné un anticorps monoclonal IgG SUB 1. Cet anticorps monoclonal a été appliqué à un ELISA en sandwich comme anticorps de capture et conjugat marqué par la phosphatase alcaline. Cette méthode permet un dosage sensible de l'anatigène anodique circulant dans les échantillons de sérum des sujets infectés détectant <1 mg d’antigène/ml de sérum. 2, record 11, French, - anticorps%20de%20capture
Record 11, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 1993-03-23
Record 12, English
Record 12, Subject field(s)
- Immunology
Record 12, Main entry term, English
- idiotypic network 1, record 12, English, idiotypic%20network
Record 12, Abbreviations, English
Record 12, Synonyms, English
Record 12, Textual support, English
Record number: 12, Textual support number: 1 CONT
Jerne's Network hypothesis. This theory, as originally formulated, stated that since the repertoire of shapes that antibodies can bind to is virtually unlimited, and since antibodies themselves have an enormous variety of idiotypic shapes, they may interact with each other specifically to form an idiotypic network. Network theory is an extension of Jerne's hypothesis proposing that lymphocytes as well as antibodies can modulate the activity of others via their receptors. 1, record 12, English, - idiotypic%20network
Record 12, French
Record 12, Domaine(s)
- Immunologie
Record 12, Main entry term, French
- réseau idiotypique
1, record 12, French, r%C3%A9seau%20idiotypique
masculine noun
Record 12, Abbreviations, French
Record 12, Synonyms, French
Record 12, Textual support, French
Record number: 12, Textual support number: 1 CONT
Le réseau idiotypique. Les anticorps sont formés d’une tige(partie Fc) associée à deux sites de reconnaissance(Fab). La partie Fc peut se fixer, par l'intermédiaire d’un récepteur spécifique, à un monocyte, un macrophage et un lymphocyte B; elle peut s’accoupler à des molécules solubles comme le complément, la protéine A du staphylocoque, etc. Le site anticorps(appelé paratope) définit l'idiotype de la molécule et reconnaît sur l'antigène un déterminant appelé épitope. Le site anticorps peut lui-même servir d’antigène pour un autre anticorps, les déterminants antigéniques de l'idiotype étant dénommés idiotypes. 1, record 12, French, - r%C3%A9seau%20idiotypique
Record 12, Spanish
Record 12, Textual support, Spanish
Record 13 - internal organization data 1991-06-14
Record 13, English
Record 13, Subject field(s)
- Immunology
Record 13, Main entry term, English
- carrier determinant
1, record 13, English, carrier%20determinant
correct
Record 13, Abbreviations, English
Record 13, Synonyms, English
Record 13, Textual support, English
Record number: 13, Textual support number: 1 CONT
The carrier determinant in the N- and C-region of hen egg-white lysozyme (lysozyme), recognized by T cells, which helps antibody formation to a single DNP residue bound to the Lysine-33 of lysozyme, was analyzed. P17 (sequence 1--27: Cys 6-CYS 127: 123--129) and P17t (sequence 1-Homoser 12; Cys 6-Cys 127: 123--129), which are known to be immunodominant antigenic determinants could induce helper T cells. When P17t was reduced and alkylated, one of the resultant peptides, P17tN (sequence 1-Homoser 12) could still induce helper T cells, but P17tC (sequence 123-129) could not. A synthetic peptide SP1-14 (sequence 1-A1a 6--14) also induced helper T cells. Thus the carrier determinant helping in antibody formation to the DNP residue at Lysine-33 may be localized in the region corresponding to the sequence 1--12 of lysozyme. 2, record 13, English, - carrier%20determinant
Record 13, French
Record 13, Domaine(s)
- Immunologie
Record 13, Main entry term, French
- épitope de la protéine porteuse
1, record 13, French, %C3%A9pitope%20de%20la%20prot%C3%A9ine%20porteuse
proposal, masculine noun
Record 13, Abbreviations, French
Record 13, Synonyms, French
Record 13, Textual support, French
Record number: 13, Textual support number: 1 OBS
Tiré de la base de données documentaire PASCAL. 2, record 13, French, - %C3%A9pitope%20de%20la%20prot%C3%A9ine%20porteuse
Record number: 13, Textual support number: 2 OBS
Équivalent proposé par Madame Josée Hamel microbiologiste au ministère Santé et Bien-Être social Canada. 1, record 13, French, - %C3%A9pitope%20de%20la%20prot%C3%A9ine%20porteuse
Record 13, Spanish
Record 13, Textual support, Spanish
Copyright notice for the TERMIUM Plus® data bank
© Public Services and Procurement Canada, 2026
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau
Features
GCtranslate (available on the Government of Canada network only)
Use this artificial intelligence prototype to translate Government of Canada content up to and including Protected B. Available to employees of selected departments and agencies only.
Writing tools
The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.
Glossaries and vocabularies
Access Translation Bureau glossaries and vocabularies.
- Date Modified:


