TERMIUM Plus®
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EPITOPE PROTEINE PORTEUSE [1 record]
Record 1 - internal organization data 1991-06-14
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- carrier determinant
1, record 1, English, carrier%20determinant
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The carrier determinant in the N- and C-region of hen egg-white lysozyme (lysozyme), recognized by T cells, which helps antibody formation to a single DNP residue bound to the Lysine-33 of lysozyme, was analyzed. P17 (sequence 1--27: Cys 6-CYS 127: 123--129) and P17t (sequence 1-Homoser 12; Cys 6-Cys 127: 123--129), which are known to be immunodominant antigenic determinants could induce helper T cells. When P17t was reduced and alkylated, one of the resultant peptides, P17tN (sequence 1-Homoser 12) could still induce helper T cells, but P17tC (sequence 123-129) could not. A synthetic peptide SP1-14 (sequence 1-A1a 6--14) also induced helper T cells. Thus the carrier determinant helping in antibody formation to the DNP residue at Lysine-33 may be localized in the region corresponding to the sequence 1--12 of lysozyme. 2, record 1, English, - carrier%20determinant
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- épitope de la protéine porteuse
1, record 1, French, %C3%A9pitope%20de%20la%20prot%C3%A9ine%20porteuse
proposal, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
Tiré de la base de données documentaire PASCAL. 2, record 1, French, - %C3%A9pitope%20de%20la%20prot%C3%A9ine%20porteuse
Record number: 1, Textual support number: 2 OBS
Équivalent proposé par Madame Josée Hamel microbiologiste au ministère Santé et Bien-Être social Canada. 1, record 1, French, - %C3%A9pitope%20de%20la%20prot%C3%A9ine%20porteuse
Record 1, Spanish
Record 1, Textual support, Spanish
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