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GANCICLOVIR [4 records]
Record 1 - internal organization data 2011-08-30
Record 1, English
Record 1, Subject field(s)
- Medication
Record 1, Main entry term, English
- ganciclovir
1, record 1, English, ganciclovir
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- ganciclovir sodium 2, record 1, English, ganciclovir%20sodium
correct
- DHPG 3, record 1, English, DHPG
correct
- DHPG sodium 4, record 1, English, DHPG%20sodium
correct
- GCV sodium 4, record 1, English, GCV%20sodium
correct
- nordeoxyguanosine 4, record 1, English, nordeoxyguanosine
correct
- Cytovene 1, record 1, English, Cytovene
correct, trademark
- Cymevene 4, record 1, English, Cymevene
correct, trademark
Record 1, Textual support, English
Record number: 1, Textual support number: 1 OBS
A drug used to treat retinitis and colitis that can result from infection with cytomegalovirus. 5, record 1, English, - ganciclovir
Record 1, French
Record 1, Domaine(s)
- Médicaments
Record 1, Main entry term, French
- ganciclovir
1, record 1, French, ganciclovir
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- ganciclovir sodique 2, record 1, French, ganciclovir%20sodique
correct, masculine noun
- DHPG 3, record 1, French, DHPG
correct, feminine noun
- DHPG 3, record 1, French, DHPG
- dihydroxypropoxyméthylguanine 3, record 1, French, dihydroxypropoxym%C3%A9thylguanine
correct, feminine noun
- Cytovene 2, record 1, French, Cytovene
correct, trademark
- Cymévan 3, record 1, French, Cym%C3%A9van
correct, trademark
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Analogue synthétique du nucléoside de la guanine qui inhibe la réplication du virus de l’herpès tant in vitro qu’in vivo. Il est utilisé pour le traitement de la rétinite à cyclomégalovirus (CMV) chez les immunodéprimés. 4, record 1, French, - ganciclovir
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Medicamentos
Record 1, Main entry term, Spanish
- ganciclovir
1, record 1, Spanish, ganciclovir
correct
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2010-04-20
Record 2, English
Record 2, Subject field(s)
- Biochemistry
- Genetics
Record 2, Main entry term, English
- herpes simplex virus thymidine kinase
1, record 2, English, herpes%20simplex%20virus%20thymidine%20kinase
correct
Record 2, Abbreviations, English
- HSV-TK 2, record 2, English, HSV%2DTK
correct
- HSV-tk 1, record 2, English, HSV%2Dtk
correct
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
In another application of gene therapy we have used an adenoviral vector that carries the gene for herpes simplex virus thymidine kinase (HSV-tk). Cells expressing HSV-tk will convert the anti-viral drug ganciclovir (GCV) to a form that is toxic to rapidly dividing cells. Using this adenoviral vector we have repeatedly shown robust tumoricidal effects in a variety of animal models of CNS tumor and will soon take this treatment to phase I clinical trials. We are extending this work to the manipulation of the CNSs immune response to tumors using adenoviral vectors that carry several cytokine genes. 1, record 2, English, - herpes%20simplex%20virus%20thymidine%20kinase
Record 2, French
Record 2, Domaine(s)
- Biochimie
- Génétique
Record 2, Main entry term, French
- thimidine kinase du virus herpès simplex
1, record 2, French, thimidine%20kinase%20du%20virus%20herp%C3%A8s%20simplex
correct, feminine noun
Record 2, Abbreviations, French
- HSV-TK 2, record 2, French, HSV%2DTK
correct, feminine noun
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Traitement du glioblastome multiforme-une tumeur létale du cerveau-par transduction tumorale in vivo du gène codant la thymidine kinase du virus herpès simplex(HSV-TK), suivie par l'administration de ganciclovir, tel est l'intitulé des essais cliniques de phase II qui ont débuté en juin dernier en Belgique. 1, record 2, French, - thimidine%20kinase%20du%20virus%20herp%C3%A8s%20simplex
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2006-06-07
Record 3, English
Record 3, Subject field(s)
- Medication
- Viral Diseases
Record 3, Main entry term, English
- aciclovir
1, record 3, English, aciclovir
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
- acyclovir 1, record 3, English, acyclovir
correct
- Zovirax 1, record 3, English, Zovirax
trademark
Record 3, Textual support, English
Record number: 3, Textual support number: 1 OBS
A guanosine analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes. 1, record 3, English, - aciclovir
Record 3, French
Record 3, Domaine(s)
- Médicaments
- Maladies virales
Record 3, Main entry term, French
- aciclovir
1, record 3, French, aciclovir
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
- acyclovir 1, record 3, French, acyclovir
correct, masculine noun
- Zovirax 1, record 3, French, Zovirax
trademark
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Les analogues des bases puriques et pyrimidiques actifs contre les virus à DNA sont l'aciclovir, le valaciclovir, le famciclovir, l'idoxuridine, la trifluridine, la vidarabine, le ganciclovir et le cidofovir. Ils sont utilisés dans le traitement des infections à virus de la famille Herpes viridae. Il s’agit de l'herpes simplex, de l'herpes zoster(zona) et des cytomégalovirus. L'aciclovir, qui s’écrit parfois acyclovir, est un analogue de la guanine substitué en position 9 par remplacement d’un atome d’hydrogène par une chaîne à fonction alcool. 1, record 3, French, - aciclovir
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Medicamentos
- Enfermedades víricas
Record 3, Main entry term, Spanish
- aciclovir
1, record 3, Spanish, aciclovir
correct, masculine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 1996-08-14
Record 4, English
Record 4, Subject field(s)
- Biotechnology
Record 4, Main entry term, English
- therapeutic gene encoding cytolytic product 1, record 4, English, therapeutic%20gene%20encoding%20cytolytic%20product
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record 4, French
Record 4, Domaine(s)
- Biotechnologie
Record 4, Main entry term, French
- gène thérapeutique cytotoxique
1, record 4, French, g%C3%A8ne%20th%C3%A9rapeutique%20cytotoxique
correct, masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Les produits des gènes thérapeutiques cytotoxiques(thymidine kinase du virus herpès associée à un traitement par le ganciclovir) ou cytostatiques(protéines Rb, Gax, eNOS) inhibent efficacement la prolifération des cellules musculaires lisses et l'hyperplasie de l'intima. 1, record 4, French, - g%C3%A8ne%20th%C3%A9rapeutique%20cytotoxique
Record 4, Spanish
Record 4, Textual support, Spanish
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