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INACTIVATEUR FONDE MECANISME [1 record]

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Record 1 2008-10-22

English

Subject field(s)
  • Molecular Biology
CONT

Mechanism-based inactivators are substrate analogues that bind to the active site of an enzyme being accepted and processed by the normal catalytic mechanism of the enzyme. During the reaction a covalent modification of the enzyme occurs leading to irreversible inactivation.

French

Domaine(s)
  • Biologie moléculaire
CONT

[...] nous avons émis l'hypothèse que la doxorubicine fonctionne comme un inactivateur fondé sur un mécanisme de la NADPH-CYP réductase [...]

Spanish

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