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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

Bisubstrate reaction in which one substrate must be bound and one product released before the entry of the second substrate and the departure of the second product. In such reactions the first substrate reacts with the enzyme to yield a chemically modified form of the latter, usually by transfer of a functional group. In the second step this functional group is transferred from the enzyme to the second substrate.  2, record 1, English, - double%2Ddisplacement%20reaction

Record number: 1, Textual support number: 1 CONT

Most two-substrate reactions can be put into one of two classes, single-displacement reactions and double-displacement reactions, which can generally be distinguished by kinetic analysis ... In bisubstrate reactions of the double-displacement type, one substrate must be bound and one product released before the entry of the second substrate and the departure of the second product.  1, record 1, English, - double%2Ddisplacement%20reaction

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Réaction à deux substrats où un substrat doit être fixé et un produit libéré avant l’entrée du second substrat et le départ du second produit. Dans de telles réactions, le premier substrat réagit avec l’enzyme pour produire une forme chimiquement modifiée de ce dernier, habituellement par transfert d’un groupement fonctionnel. Dans la seconde étape, ce groupe fonctionnel est transféré de l’enzyme au second substrat.  2, record 1, French, - r%C3%A9action%20%C3%A0%20double%20d%C3%A9placement

Record number: 1, Textual support number: 1 CONT

Un exemple d’une [...] réaction à double déplacement est donné par l'aspartate aminotransférase, encore appelée aspartate transaminase. [...] L'aspartate se combine en premier avec l'enzyme. Le radical aminé de l'aspartate est ensuite transféré au groupement prosthétique de l'enzyme, le phosphate de pyridoxal. Le premier produit, l'oxaloacétate, quitte alors le site actif et est remplacé par le second substrat, l'[alpha]-cétoglutarate, sur lequel le radical aminé est transféré pour former le glutamate qui, ensuite, quitte le site actif.  1, record 1, French, - r%C3%A9action%20%C3%A0%20double%20d%C3%A9placement

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

The tricarboxylic-acid-cycle enzyme which catalyses the synthesis of citrate from oxaloacetate and acetyl-coenzyme A in an aldol condensation.  3, record 2, English, - citrate%20synthase

Record number: 2, Textual support number: 1 CONT

Biopsies of the vastus lateralis muscle showed increases in mean fiber area capillaries per fiber and citrate synthase activity but no change in fiber type distribution.  4, record 2, English, - citrate%20synthase

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

La condensation initiale de l'acétyl-CoA avec l'oxaloacétate pour former le citrate est catalysée par une enzyme condensante, la citrate synthase, qui forme une liaison C-C entre le carbone du groupement méthyle de l'acétyl-CoA et le carbone du groupement carbonyle de l'oxaloacétate.  1, record 2, French, - citrate%20synthase

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

a salt of oxaloacetic acid.  2, record 3, English, - oxaloacetate

Record number: 3, Textual support number: 1 CONT

In C4 plants ... carbon dioxide is fixed ... into ... oxaloacetate, an acid with four carbon atoms.  3, record 3, English, - oxaloacetate

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Sel de l’acide oxaloacétique.  2, record 3, French, - oxaloac%C3%A9tate

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

Enzyme that catalyzes the reversible reduction of oxaloacetic acid to malic acid in a reaction linked to the oxidation-reduction of NAD.  2, record 4, English, - malate%20dehydrogenase

Record number: 4, Textual support number: 1 OBS

Because of technical constraints, the formula(s) given in CBT-167 could not be reproduced.  3, record 4, English, - malate%20dehydrogenase

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Enzyme catalysant la réaction de déshydrogénation du L-malate en oxaloacétate.  2, record 4, French, - malate%20d%C3%A9shydrog%C3%A9nase

Record 4,  Textual support,  Spanish