TERMIUM Plus®

From: Translation Bureau

On social media

Consult the Government of Canada’s terminology data bank.

TUMORIGENICITE [1 record]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2002-01-08

English

Subject field(s)
  • Cytology
CONT

The primary interest of this laboratory is in the mechanism of cell transformation and oncogenicity of receptor protein tyrosine kinases (RPTKs). Currently, we are studying the ros oncogene, originally discovered in an avian sarcoma virus, human insulin receptor (IR) and human insulin-like growth factor I receptor (IGFR). Molecular basis for the oncogenic activation as well as signalling transduction pathways responsible for normal and oncogenic functions of those receptor PTKs are being explored. Regulation and intervention of those oncogenic RPTKs by potential suppressor "anti-oncogene" such as protein tyrosine phosphatase (PTPase) and dominant-negative mutants of downstream signalling molecules are being inquired. Finally, potential role of those and other RPTKs in the development and progression of human malignancy, particularly breast cancer, are also being examined.

French

Domaine(s)
  • Cytologie
CONT

[...] les cellules utilisées doivent être soumises à des épreuves de tumorigénicité [...]. Bien que les techniques biochimiques permettent un dosage assez précis de la quantité d’ADN dans le produit fini, une mesure indépendante de la tumorigénicité potentielle doit être également fournie.

Spanish

Save record 1

Copyright notice for the TERMIUM Plus® data bank

© Public Services and Procurement Canada, 2026
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau

Display options

Change the order of display of the official languages of Canada
Option to display the non-official languages (Spanish or Portuguese)
Display definitions, contexts, etc., on records

Features

GCtranslate (available on the Government of Canada network only)

Use this artificial intelligence prototype to translate Government of Canada content up to and including Protected B. Available to employees of selected departments and agencies only.

Writing tools

The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.

Glossaries and vocabularies

Access Translation Bureau glossaries and vocabularies.

Date Modified: