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BOUCLE AMPLIFICATION [1 record]

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Record 1 2006-02-27

English

Subject field(s)
  • Immunology
DEF

The alternative complement activation pathway which acts as a positive feedback loop when C3 is split in the presence of an activator surface.

French

Domaine(s)
  • Immunologie
CONT

Une fois activée, la voie alterne est accélérée par une boucle d'amplification qui aboutit à la formation d'une C3 convertase à laquelle s'oppose un puissant système inhibiteur. Formation de la C3 convertase alterne. La boucle d'amplification met en jeu trois des six protéines de la voie alterne : le C3, le B et le D. [...] Boucle d'amplification de la voie alterne : chaque molécule de C3b peut, en présence du B et du D, former un C3 convertase (C3bBb) capable de cliver le C3 en C3b et C3a.

Spanish

Campo(s) temático(s)
  • Inmunología
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