TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

CITRATE 1-{[3-(6 7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO[4 3-D]PYRIMIDIN-5-YL)-4-ETHOXYPHENYL]SULFONYL}-4-METHYLPIPERAZINE [2 records]

Record 1 2011-04-26

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
C22H30N6O4S
formula, see observation
139755-83-2
CAS number
CONT

Sildenafil, ... was discovered through a rational drug design programme by the pharmaceutical company Pfizer. It is a potent selective inhibitor of the enzyme phosphodiesterase (PDE-5), which destroys cyclic guanosine monophosphate (cGMP), itself a dilator of blood vessels in the body.

OBS

sildenafil: International nonproprietary name (INN) of the World Health Organization (WHO).

OBS

The capital letter "H" and the small letter "d" between brackets must be italicized.

OBS

Chemical formula: C22H30N6O4S

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
C22H30N6O4S
formula, see observation
139755-83-2
CAS number
OBS

sildénafil : Dénomination commune internationale (DCI) de l'Organisation mondiale de la santé (OMS).

OBS

La lettre majuscule «H» et la lettre minuscule «d» entre crochets s'écrivent en italique.

OBS

Formule chimique : C22H30N6O4S

Spanish

Save record 1

Record 2 2011-03-18

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
C22H30N6O4S
formula, see observation
171599-83-0
CAS number
DEF

An oral drug for men with erectile dysfunction that is being developed by Pfizer.

CONT

Viagra it is an orally active, selective inhibitor of type-V phosphodiesterase, the predominant isoenzyme causing the inactivation of cyclic guanosine monophosphate (cGMP) in the human corpus cavernosum. Researchers have learned that nitric oxide (NO) is the principal neurotransmitter in the penis. NO is influenced by testosterone and androgens, and penile erection is mediated by NO via cGMP. Viagra produces its pro-erectile effect through increasing cGMP levels.

OBS

sidenafil citrate: International nonproprietary name (INN) of the World Health Organization (WHO).

OBS

The capital letter "H" and the small letter "d" between brackets must be italicized.

OBS

Chemical formula: C22H30N6O4S

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
C22H30N6O4S
formula, see observation
171599-83-0
CAS number
DEF

Agent de la thérapie orale de la dysfonction érectile.

CONT

Les pilules de Viagra contiennent 25 mg, 50 mg ou 100 mg de sildénafil sous forme de citrate [...]

OBS

citrate de sildénafil : Dénomination commune internationale (DCI) de l'Organisation mondiale de la santé (OMS).

OBS

La lettre majuscule «H» et la lettre minuscule «d» entre crochets s'écrivent en italique.

OBS

Formule chimique : C22H30N6O4S

Spanish

Save record 2

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