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GELATINASE B [1 record]

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Record 1 2014-01-22

English

Subject field(s)
  • Biochemistry
CONT

Biological studies of MMP-9 have tuned the field from being primarily cancer-oriented towards vascular and inflammatory research. In tumor biology, it has been increasingly appreciated that MMP-9 from inflammatory cells, particularly neutrophils, co-determines prognosis and outcome.

Key term(s)
  • MMP9

French

Domaine(s)
  • Biochimie
CONT

La métalloprotéinase matricielle-9, également appelée gélatinase B, est sécrétée dans l’espace extracellulaire sous une forme zymogène par les polynucléaires neutrophiles, les monocytes/macrophages, les (myo)fibroblastes, les myocytes et les cellules endothéliales. Son principal substrat est la gélatine B (forme de collagène dénaturé).

Key term(s)
  • MMP9

Spanish

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