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GENE PTC [1 record]

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Record 1 1997-07-10

English

Subject field(s)
  • Genetics
CONT

The overlap between gene pathways controlling embryonic development and those involved in regulating cell proliferation are becoming very compelling. A new celebrity that performs in both of these is the human patched gene, which plays many roles during development and now makes an entrance as a tumor suppressor. The evidence exposing this latest alias of «patched», a faulty version of which is associated with a complex of cancers kwown as nevoid basal cell-carcinoma (NBCC) syndrome was described last month in Cell and Science.

French

Domaine(s)
  • Génétique
CONT

Nous avons déjà vu que des mutations du gène «patched» (PTC), codant pour un récepteur de Sonic Hedgehog, étaient à l'origine de la naevomatose basocellulaire de Gorlin.

Spanish

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