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GLOBULINE ANTILYMPHOCYTE [1 record]

Record 1 2011-01-05

English

Subject field(s)
  • Immunology
DEF

An antibody directed against lymphocyte surface antigens. Such antibodies are produced by immunization of experimental animals with heterologous lymphocytes and are used ... for example in organ transplantation.

Key term(s)
  • anti-lymphocyte globulin

French

Domaine(s)
  • Immunologie
DEF

Immunoglobuline (anticorps) d'origine animale (lapin, chèvre ou cheval) générée en réponse à l'immunisation (de l'animal en question) par des lymphocytes humains.

OBS

La globuline anti-lymphocytaire (ou sérum anti-lymphocytaire ou anti-thymocyte) est [...] utilisée, en association avec la cortisone et la cyclosporine-A, comme traitement de première instance dans les aplasies médullaires. [...] Lorsqu'injecté chez l'homme, ce sérum (ou globuline) peut détruire les lymphocytes auto-réactifs responsables de l'aplasie et ainsi contribuer à la correction de la maladie.

Spanish

Campo(s) temático(s)
  • Inmunología
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