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GRAMICIDINE [3 records]

Record 1 2003-05-15

English

Subject field(s)
  • Microbiology and Parasitology
  • Pharmacy
  • Biotechnology
DEF

A polypeptide antibacterial antibiotic produced by Bacillus brevis; active locally against gram-positive bacteria.

French

Domaine(s)
  • Microbiologie et parasitologie
  • Pharmacie
  • Biotechnologie
DEF

Antibiotique, isolé de la tyrothricine, actif sur les germes Gram positifs.

OBS

«Gramacidin» : Gramicidin (Lundbeck)

OBS

«Gramicidine» : Gramicidine (Sobio)

OBS

«Gramidine» : Gramidine (Sobio)

OBS

«Gramoderm» : Gramoderm (Schering)

Spanish

Campo(s) temático(s)
  • Microbiología y parasitología
  • Farmacia
  • Biotecnología
DEF

Cada uno de los antibióticos del grupo producido por Bacillus brevis. Su estructura química responde a la de péptidos cíclicos. El constituyente más importante del grupo, gramicidina S, es un decapéptido cíclico. El mecanismo de acción reside en su comportamiento desacoplador de la fosforilación oxidativa.

Save record 1

Record 2 2002-08-20

English

Subject field(s)
  • Microbiology and Parasitology
  • Pharmacy

French

Domaine(s)
  • Microbiologie et parasitologie
  • Pharmacie

Spanish

Campo(s) temático(s)
  • Microbiología y parasitología
  • Farmacia
Save record 2

Record 3 1980-09-01

English

Subject field(s)
  • Biochemistry
OBS

Ionophores, molecules that carry ions across [mitochondrial] membranes, are essential tools in the study of chemiosmotic mechanisms (...) The ionophore valinomy is a cyclic molecule that is soluble in membranes and selectively carries potassium ions (K+). Nigericin also transports potassium, but only in exchange for protons; it is insoluble in the membrane unless one ion or the other is bound. Gramicidin A forms a pore in the membrane, made up of two helical molecules, that is permeable to ions with one positive charge.

French

Domaine(s)
  • Biochimie
OBS

Les ionophores, molécules qui transportent les ions à travers les membranes (mitochondriales) sont des outils essentiels dans l'étude des mécanismes chimiosmotiques [...] La valinomycine est un ionophore; c'est une molécule cyclique qui est soluble dans les membranes et transporte sélectivement les ions potassium (K+). La nigécirine transporte aussi le potassium mais seulement en l'échangeant avec des protons; elle est insoluble dans la membrane sauf lorsqu'elle est liée à l'un de ces ions. Deux molécules hélicoïdales de gramicidine A forment un pore à travers la membrane perméable aux ions porteurs d'une seule charge positive.

Spanish

Save record 3

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