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IMMUNOPEPTIDOME [1 record]

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Record 1 2014-10-29

English

Subject field(s)
  • Immunology
CONT

Self/non-self discrimination is a fundamental requirement of life. Endogenous peptides presented by major histocompatibility complex class I (MHC I) molecules represent the essence of self for CD8 T lymphocytes. These MHC I peptides (MIPs) are collectively referred to as the immunopeptidome.

French

Domaine(s)
  • Immunologie
CONT

La différentiation entre le «soi» et le «non-soi» est un processus biologique essentiel à la vie. Les peptides endogènes présentés par les complexes majeurs d’histocompatibilité de classe I (CMH I) représentent le fondement du «soi» pour les lymphocytes T CD8+. On donne le nom d’immunopeptidome à l’ensemble des peptides présentés à la surface cellulaire par les molécules du CMH I.

Spanish

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