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VNTR [1 record]
Record 1 - internal organization data 2010-05-13
Record 1, English
Record 1, Subject field(s)
- Genetics
- Biotechnology
Record 1, Main entry term, English
- variable number of tandem repeats
1, record 1, English, variable%20number%20of%20tandem%20repeats
correct
Record 1, Abbreviations, English
- VNTR 2, record 1, English, VNTR
correct
Record 1, Synonyms, English
- short tandem repeat polymorphism 3, record 1, English, short%20tandem%20repeat%20polymorphism
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Short tandem repeat polymorphisms, also referred to as variable number of tandem repeats (VNTRs), are very important to scientists, because they can be used to identify individuals genetically. Marker systems are used to detect loci that respond to restriction enzyme cleavage by producing a fragment that can have many different lengths. This polymorphism is due to variation in the number of tandem repeats. VNTRs can be identified in various ways. Probes can be developed which will hybridize to complementary sequences after RFLP has been performed on a sample of genomic DNA (Southern blots). A second method involves the use of PCR. If the sequence surrounding the VNTR is known, PCR primers (oligonucleotides) can be designed to amplify the repeat region(s). The information obtained from these experiments is useful in the fields of forensics, population characterization, human gene mapping, identification of genes involved in disease, relationship testing, and identifying genes of interest such as those that encode proteins containing zinc finge. 3, record 1, English, - variable%20number%20of%20tandem%20repeats
Record 1, French
Record 1, Domaine(s)
- Génétique
- Biotechnologie
Record 1, Main entry term, French
- nombre variable de répétitions en tandem
1, record 1, French, nombre%20variable%20de%20r%C3%A9p%C3%A9titions%20en%20tandem
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- VNTR 2, record 1, French, VNTR
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Ces expertises sont actuellement effectuées par l'analyse de l'ADN (Acide DésoxyriboNucléique) au moyen de l'examen du polymorphisme VNTR (Variable Number of Tandem Repeats) qui est un polymorphisme de restriction (RFLP = Restriction Fragments Length Polymorphism). Un VNTR est un polymorphisme de répétition ou de longueur. Il s'agit d'une séquence répétée qui constitue un allèle, dont le nombre de répétitions varie d'un individu à l'autre, et qui se transmet selon les lois de Mendel. Chez un hétérozygote les deux allèles sont visibles; il s'agit donc de marqueurs génétiques co-dominants. 2, record 1, French, - nombre%20variable%20de%20r%C3%A9p%C3%A9titions%20en%20tandem
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
- Biotecnología
Record 1, Main entry term, Spanish
- repeticiones en tándem de número variable
1, record 1, Spanish, repeticiones%20en%20t%C3%A1ndem%20de%20n%C3%BAmero%20variable
correct, feminine noun
Record 1, Abbreviations, Spanish
- RTNV 2, record 1, Spanish, RTNV
correct, feminine noun
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Secuencias repetidas de ADN, organizadas en tándem, cuyo número de copias es muy variable según el genotipo. 3, record 1, Spanish, - repeticiones%20en%20t%C3%A1ndem%20de%20n%C3%BAmero%20variable
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