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The Government of Canada’s terminology and linguistic data bank.
CD4 SOLUBLE [2 records]
Record 1 - internal organization data 2005-02-21
Record 1, English
Record 1, Subject field(s)
- Microbiology and Parasitology
- Biochemistry
Record 1, Main entry term, English
- recombinant soluble CD4
1, record 1, English, recombinant%20soluble%20CD4
correct
Record 1, Abbreviations, English
- rCD4 1, record 1, English, rCD4
correct
- rsCD4 1, record 1, English, rsCD4
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Recombinant soluble CD4 (rsCD4, rCD4): rCD4 is a soluble form of the CD4 receptors attached to the surface of T4 cells. rCd4 is produced by recombinant DNA biotechnology using mammalian and insect cell lines. HIV binds to CD4 in order to gain entry into the cells. The hope is that rsCd4 when given to patients, will bind to the virus and neutralize it. 1, record 1, English, - recombinant%20soluble%20CD4
Record 1, French
Record 1, Domaine(s)
- Microbiologie et parasitologie
- Biochimie
Record 1, Main entry term, French
- CD4 soluble recombinée
1, record 1, French, CD4%20soluble%20recombin%C3%A9e
correct, feminine noun
Record 1, Abbreviations, French
- rCD4 2, record 1, French, rCD4
feminine noun
Record 1, Synonyms, French
- CD4 soluble recombinée 1, record 1, French, CD4%20soluble%20%20recombin%C3%A9e
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
La protéine CD4 soluble, synthétisée par génie génétique, pourrait servir de leurre-chélateur du V.I.H. Elle se fixerait sur la gp120 du V.I.H.,empêchant sa liaison sur le récepteur membranaire des lymphocytes T4. De nombreuses formes de CD4 solubles ont été obtenues par la technologie de l'ADN recombinant (rCD4). Ces rCD4 inhibent l'infection par le VIH, ainsi que la réplication de la fusion cellulaire induite par le VIH. (D'après les sources c et d). 1, record 1, French, - CD4%20soluble%20recombin%C3%A9e
Record number: 1, Textual support number: 2 OBS
Recombinant ou mieux encore recombiné: qui est synthétisé par génie génétique. 1, record 1, French, - CD4%20soluble%20recombin%C3%A9e
Record 1, Key term(s)
- CD4 soluble recombinante
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Microbiología y parasitología
- Bioquímica
Record 1, Main entry term, Spanish
- CD4 soluble recombinante
1, record 1, Spanish, CD4%20soluble%20recombinante
feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2001-09-14
Record 2, English
Record 2, Subject field(s)
- Genetics
- Human Diseases
Record 2, Main entry term, English
- soluble CD4
1, record 2, English, soluble%20CD4
correct
Record 2, Abbreviations, English
- sCD4 1, record 2, English, sCD4
correct
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
A soluble form of the CD4 receptor can either enhance or inhibit the infection of cells by simian immunodeficiency virus (SIV) and human immunodeficiency virus. 1, record 2, English, - soluble%20CD4
Record 2, French
Record 2, Domaine(s)
- Génétique
- Maladies humaines
Record 2, Main entry term, French
- CD4 soluble
1, record 2, French, CD4%20soluble
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Principales stratégies de thérapie génique de l'infection par le VIH : CD4 soluble bloquant la fixation des particules sur le récepteur CD4 [...]. 2, record 2, French, - CD4%20soluble
Record 2, Spanish
Record 2, Textual support, Spanish
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