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HYPOGAMMAGLOBULINEMIE EXPRESSION VARIABLE [1 record]
Record 1 - internal organization data 1993-02-16
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- common variable immunodeficiency 1, record 1, English, common%20variable%20immunodeficiency
Record 1, Abbreviations, English
Record 1, Synonyms, English
- common variable unclassifiable immunodeficiency 1, record 1, English, common%20variable%20unclassifiable%20immunodeficiency
- acquired agammaglobulinemia 1, record 1, English, acquired%20agammaglobulinemia
- common variable agammaglobulinemia 1, record 1, English, common%20variable%20agammaglobulinemia
- common variable hypogammaglobulinemia 1, record 1, English, common%20variable%20hypogammaglobulinemia
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A heterogeneous group of disorders characterized by hypogamma-globulinemia, decreased antibody production in response to antigenic challenge, and recurrent pyogenic infections, and often associated with hematologic and autoimmune disorders. Most patients have normal numbers of circulating B cells but lack plasma cells, and are thus thought to have an intrinsic defect of B cell differentiation. Many also have T cell defects and exhibit cutaneous energy to recall antigens. 1, record 1, English, - common%20variable%20immunodeficiency
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- hypogammaglobulinémie à expression variable
1, record 1, French, hypogammaglobulin%C3%A9mie%20%C3%A0%20expression%20variable
feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Hypogammaglobulinémie à expression variable. On regroupe sous ce terme des déficits immunitaires très fréquents, en général non héréditaires, ayant en commun un abaissement de la concentration des Ig sériques (variables selon la classe), contrastant avec un taux normal de cellules B dans le sang. L'atteinte des cellules T est variable selon les patients mais en règle générale modeste. Les cellules B sont incapables de se différencier en plasmocytes en présence de pokeweed. 1, record 1, French, - hypogammaglobulin%C3%A9mie%20%C3%A0%20expression%20variable
Record 1, Spanish
Record 1, Textual support, Spanish
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