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LYMPHOHISTIOCYTOSE HEMOPHAGOCYTAIRE SECONDAIRE [1 record]
Record 1 - internal organization data 2023-03-30
Record 1, English
Record 1, Subject field(s)
- Human Diseases - Various
- Blood
Record 1, Main entry term, English
- secondary hemophagocytic lymphohistiocytosis
1, record 1, English, secondary%20hemophagocytic%20lymphohistiocytosis
correct
Record 1, Abbreviations, English
- SHLH 2, record 1, English, SHLH
correct, see observation
Record 1, Synonyms, English
- acquired hemophagocytic lymphohistiocytosis 3, record 1, English, acquired%20hemophagocytic%20lymphohistiocytosis
correct
- secondary HLH 4, record 1, English, secondary%20HLH
correct
- acquired HLH 5, record 1, English, acquired%20HLH
correct, rare
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Secondary hemophagocytic lymphohistiocytosis [HLH] (ie, acquired hemophagocytic lymphohistiocytosis) occurs after strong immunologic activation, such as that which can occur with systemic infection, immunodeficiency, or underlying malignancy. [Like primary HLH, it is] characterized by the overwhelming activation of normal T lymphocytes and macrophages, invariably leading to clinical and hematologic alterations and death in the absence of treatment. 6, record 1, English, - secondary%20hemophagocytic%20lymphohistiocytosis
Record number: 1, Textual support number: 1 OBS
SHLH is also the abbreviation of "sporadic hemophagocytic lymphohistiocytosis." 7, record 1, English, - secondary%20hemophagocytic%20lymphohistiocytosis
Record 1, French
Record 1, Domaine(s)
- Maladies humaines diverses
- Sang
Record 1, Main entry term, French
- lymphohistiocytose hémophagocytaire secondaire
1, record 1, French, lymphohistiocytose%20h%C3%A9mophagocytaire%20secondaire
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- LH secondaire 1, record 1, French, LH%20secondaire
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les LH secondaires sont liées à différents états pathologiques (infections en particulier, ainsi qu'affections néoplasiques et auto-immunes) qui aboutissent au tableau de LH à cause d'un déficit acquis des fonctions cytotoxiques des lymphocytes T et des cellules «natural killer». Les critères diagnostiques sont [...] pour les LH secondaires, l'existence d'au moins cinq des huit critères suivants : fièvre, splénomégalie, cytopénies affectant deux lignées ou plus, hypertriglycéridémie et/ou hypofibrinogénémie, hémophagocytose dans la moelle osseuse, la rate ou les ganglions lymphatiques, activité «natural killer» diminuée ou absente, hyperferritinémie, augmentation du récepteur soluble de l'interleukine 2. 1, record 1, French, - lymphohistiocytose%20h%C3%A9mophagocytaire%20secondaire
Record 1, Spanish
Record 1, Textual support, Spanish
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