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MALADIE MONOGENIQUE [2 records]
Record 1 - internal organization data 2004-08-23
Record 1, English
Record 1, Subject field(s)
- Biotechnology
Record 1, Main entry term, English
- single-gene disorder
1, record 1, English, single%2Dgene%20disorder
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- single-gene disease 2, record 1, English, single%2Dgene%20disease
correct
- monogenic disease 3, record 1, English, monogenic%20disease
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Genetic disorder caused by an anomaly in a single gene. 4, record 1, English, - single%2Dgene%20disorder
Record 1, French
Record 1, Domaine(s)
- Biotechnologie
Record 1, Main entry term, French
- maladie monogénique
1, record 1, French, maladie%20monog%C3%A9nique
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Maladie due à une anomalie dans la structure (ou la séquence) d'un seul gène. 1, record 1, French, - maladie%20monog%C3%A9nique
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 1997-03-20
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- monogenic hereditary disease
1, record 2, English, monogenic%20hereditary%20disease
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
The foundation for our current studies has been a detailed investigation of the molecular genetics of retinoblastoma, a paradigm for familial cancer predisposition and a classic monogenic hereditary disease. 1, record 2, English, - monogenic%20hereditary%20disease
Record number: 2, Textual support number: 1 OBS
monogenic character: a character determined by a single gene. 2, record 2, English, - monogenic%20hereditary%20disease
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- maladie héréditaire monogénique
1, record 2, French, maladie%20h%C3%A9r%C3%A9ditaire%20monog%C3%A9nique
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Surtout, on entrevoit de claires indications à la thérapie génique. À côté des maladies héréditaires monogéniques, où l'on compte quelques succès (déficit ADA, mucopolysaccharidoses) et des échecs temporaires (muscovidose), l'intérêt de la thérapie génique s'est vite déplacée vers les maladies acquises polygéniques comme le cancer. 1, record 2, French, - maladie%20h%C3%A9r%C3%A9ditaire%20monog%C3%A9nique
Record number: 2, Textual support number: 1 OBS
Génétique moléculaire. 2, record 2, French, - maladie%20h%C3%A9r%C3%A9ditaire%20monog%C3%A9nique
Record 2, Spanish
Record 2, Textual support, Spanish
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