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PLEIOTROPIE [2 records]
Record 1 - internal organization data 2012-07-18
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- pleiotropy
1, record 1, English, pleiotropy
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The effects of a single gene or a pair of genes on more than one phenotype. 2, record 1, English, - pleiotropy
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- pléiotropie
1, record 1, French, pl%C3%A9iotropie
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Expression de plusieurs caractères différents à partir de l'information portée par un seul gène. 2, record 1, French, - pl%C3%A9iotropie
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
Record 1, Main entry term, Spanish
- pleiotropía
1, record 1, Spanish, pleiotrop%C3%ADa
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- pleitropía 2, record 1, Spanish, pleitrop%C3%ADa
feminine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Efecto simultáneo de un determinado gen sobre dos o más caracteres aparentemente no relacionados. 3, record 1, Spanish, - pleiotrop%C3%ADa
Record 2 - internal organization data 2008-09-26
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- antagonistic pleiotropy
1, record 2, English, antagonistic%20pleiotropy
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- antagonistic pleitropy 2, record 2, English, antagonistic%20pleitropy
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 OBS
This is central to a theory of aging first developed by G. C. Williams in 1957. Williams suggested that some genes responsible for increased fitness in the younger, fertile organism contribute to decreased fitness later in life. One such example in male humans is the gene for the hormone testosterone. In youth, testosterone has positive effects including reproductive fitness but, later in life, there are negative effects such as increased susceptibility to prostate cancer. 1, record 2, English, - antagonistic%20pleiotropy
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- pléiotropie antagoniste
1, record 2, French, pl%C3%A9iotropie%20antagoniste
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
[...] la pléiotropie antagoniste a été proposée en 1957 par Williams. Comme son nom l'indique, elle fait appel à des mutations pléiotropes, c'est-à-dire capables d'influencer plusieurs caractères structuraux ou fonctionnels d'un même organisme. Les mutations envisagées par l'auteur ont des effets contrastés sur les individus en fonction de leur âge: elles favorisent la viabilité des individus jeunes, mais affaiblissent les individus âgés. La sélection naturelle aurait retenu ces mutations parce que les avantages qu'elles procurent aux jeunes l'emportent sur les inconvénients qu'elles occasionnent chez les vieux. 1, record 2, French, - pl%C3%A9iotropie%20antagoniste
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Genética
Record 2, Main entry term, Spanish
- pleiotropía antagónica
1, record 2, Spanish, pleiotrop%C3%ADa%20antag%C3%B3nica
correct, feminine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 CONT
[...] en nuestra especie, la fatiga [...] devino entre otras en climaterio; es decir que este, surgido como consecuencia de los mecanismos por los que se produce la adaptación (respuesta debida y adquisición de nuevos genes), bien podría corresponder a la llamada pleiotropía antagónica que hace que alelos adoptados, por comportar alguna mejora adaptativa en edad temprana, puedan tornarse destructivos en fases tardías de la vida. 1, record 2, Spanish, - pleiotrop%C3%ADa%20antag%C3%B3nica
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