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PROTO-ONCOGENE [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2024-02-29

English

Subject field(s)
  • Genetics
DEF

A normal gene that with slight alteration by mutation or other mechanism becomes an oncogene.

French

Domaine(s)
  • Génétique
DEF

Gène existant dans le génome d'une cellule et pouvant devenir oncogène à la suite d'une activation consécutive à une mutation, une translocation ou à l'insertion d'un promoteur viral actif.

OBS

Les produits de ces gènes cellulaires participent normalement aux communications intra- ou intercellulaires.

Spanish

Campo(s) temático(s)
  • Genética
DEF

[...] gen [normal] que puede convertirse en oncogén por una mutación.

OBS

protoncogén: La Fundación del Español Urgente (Fundéu BBVA), con el asesoramiento de la Real Academia Española, indica que los términos "oncogén" y "protooncogén" se escriben con tilde por ser palabras agudas que terminan en ene. [...] Se aplica lo mismo para "protooncogén", que se refiere a los genes cuya mutación o amplificación da lugar a un "oncogén". En este caso, también es válida, aunque menos frecuente, la grafía "protoncogén", con una sola o. Sus plurales son "protooncogenes" y "protoncogenes", respectivamente.

Save record 1

Record 2 2012-07-31

English

Subject field(s)
  • Cytology
  • Genetics
DEF

A proto-oncogene that has been activated within the host so that oncogenicity results.

OBS

proto-oncogene: a normal cellular gene that with alteration, such as by mutation, DNA rearrangement, or nearby insertion of viral DNA, becomes an active oncogene; most proto-oncogenes are believed to normally function in cell growth and differentiation.

Key term(s)
  • c onc

French

Domaine(s)
  • Cytologie
  • Génétique
CONT

Les oncogènes cellulaires (c-onc) correspondent à la version mutée de gènes intervenant dans de nombreuses fonctions normales de la cellule, et les oncogènes viraux (v-onc) sont constitués par des gènes cellulaires qui ont été jadis empruntés par les rétrovirus.

Key term(s)
  • c onc

Spanish

Campo(s) temático(s)
  • Citología
  • Genética
Save record 2

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