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PROPOSITO [1 record]
Record 1 - internal organization data 2020-06-05
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- proband
1, record 1, English, proband
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- propositus 2, record 1, English, propositus
correct
- index case 3, record 1, English, index%20case
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The original person presenting with, or likely to be subject to, a mental or physical disorder and whose case serves as the stimulus for a hereditary or genetic study. 4, record 1, English, - proband
Record number: 1, Textual support number: 1 OBS
In genetics, the index case is the case of the original patient (i.e. propositus or proband) that stimulates investigation of other members of the family to discover a possible genetic factor. 5, record 1, English, - proband
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- proposant
1, record 1, French, proposant
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- propositus 2, record 1, French, propositus
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Malade qui consulte le premier pour une affection génétique et qui déclenche une enquête génétique dans sa famille afin de déterminer le mode de transmission de cette affection. 2, record 1, French, - proposant
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
Record 1, Main entry term, Spanish
- probando
1, record 1, Spanish, probando
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- caso índice 2, record 1, Spanish, caso%20%C3%ADndice
correct, masculine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
El probando es aquel miembro de la familia vivo que ha desarrollado cáncer en el que existen las mayores probabilidades de encontrar una mutación y por quien debe iniciarse el estudio genético. 3, record 1, Spanish, - probando
Record number: 1, Textual support number: 2 CONT
En general, el primer individuo que se diagnostica dentro de una familia se denomina caso índice o probando. A partir de su diagnóstico, se debe realizar una evaluación clínica en cascada de los familiares, empezando por los de primer grado (progenitores, hermanos, hijos). 2, record 1, Spanish, - probando
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