TERMIUM Plus®

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KILLER CELL INHIBITORY RECEPTOR [1 record]

Record 1 2000-05-17

English

Subject field(s)
  • Immunology
  • Cytology
CONT

Multiple genes encoding type I transmembrane molecules and belonging to the immunoglobulin superfamily have recently been localized to human chromosome 19q13.4. These include a family of genes encoding killer cell inhibitory receptors (KIR)expressed on natural killer (NK) cells and subsets of T-lymphocytes, immunoglobulin-like transcripts (ILT-1, -2 and 3) expressed on myeloid cells and subsets of lymphoid cells, the gp49 family of receptors expressed on mast cells and NK cells and the gene encoding human myeloid immunoglobulin A Fc receptor (CD89).

French

Domaine(s)
  • Immunologie
  • Cytologie
CONT

[...] l'identification et la caractérisation des récepteurs de types inhibiteurs spécifiques des allèles du CMH de classe 1 (KIR, killer cell inhibitory receptor) ont permis de comprendre les mécanismes de reconnaissance spécifique et de lyse de cellules tumorales ayant perdu l'expression de certaines molécules de classe 1.

Spanish

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