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ANGIOTROPIN [1 record]

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Record 1 1998-11-02

English

Subject field(s)
  • Blood
  • Biochemistry
CONT

Purified monocyte-derived angiogenic substance (angiotropin) stimulates migration, phenotypic changes, and "tube formation" but not proliferation of capillary endothelial cells in vitro.

French

Domaine(s)
  • Sang
  • Biochimie
CONT

L'angiotropine est un polyribonucléopolypeptide contenant du cuivre, isolé à partir de cultures de monocytes activés. Ce facteur également non mitogène est un puissant agent de différenciation des cellules capillaires; il induit la formation de tubes; il stimule aussi la migration des cellules endothéliales microvasculaires. Le recrutement des monocytes-macrophages au sein d'un foyer tumoral pourrait avoir pour conséquence une libération d'angiotropine et stimuler de la sorte l'angiogénèse.

Spanish

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