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INSULIN-RECEPTOR SUBSTRATE 1 [1 record]

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Record 1 2011-11-02

English

Subject field(s)
  • Genetics
CONT

In mammals, one major insulin receptor substrate (IRS1) has been identified as a docking protein which, following tyrosine phosphorylation, is able to interact with several intracellular proteins which, in a cascade, activate most of, if not all, the metabolic and mitogenic pathways controlled by insulin.

French

Domaine(s)
  • Génétique
CONT

Le récepteur [...] IGF1 est une tyrosine kinase dont le substrat principal est un peptide cytoplasmique désigné IRS1 (insulin-receptor substrate-1] parce qu'il est également substrat du récepteur de l'insuline.

Spanish

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