TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

TUMOR NECROSIS FACTOR [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2021-02-26

English

Subject field(s)
  • Cytology
  • Immunology
  • Medication
DEF

A protein produced by macrophages in response to bacterial infection ...

CONT

Tumor necrosis factor (TNF) was originally discovered as a serum protein with necrotizing effects on certain transplantable mouse tumors in vivo and cytotoxic effects against some transformed cells in vitro. The TNF family consists of two proteins designated TNF-alpha, also called cachectin, and TNF-beta, also called lymphotoxin, which are pleiotropic cytokines that can mediate a wide variety of biological effects. TNF-beta is produced by activated lymphocytes, whereas TNF-alpha is mostly produced by activated macrophages.

OBS

A form made by genetic engineering is used in [some treatments].

OBS

In specialized works, the term «tumour necrosis factor» often makes reference to the tumour necrosis factor alpha.

French

Domaine(s)
  • Cytologie
  • Immunologie
  • Médicaments
CONT

Au cours des dernières années, on a mis en évidence un nombre croissant de protéines intervenant dans l'inflammation et l'immunité comme la croissance et l'inhibition cellulaires. Ces protéines, auxquelles on a donné le nom général de cytokines, comprennent […] le TNF […]

OBS

[…] on connaît actuellement la séquence du TNF de plusieurs espèces et on le fabrique par génie génétique.

OBS

Dans les ouvrages spécialisés, le terme «facteur de nécrose tumorale» fait souvent référence au facteur de nécrose tumorale alpha.

Spanish

Campo(s) temático(s)
  • Citología
  • Inmunología
  • Medicamentos
DEF

Polipéptido que interviene en los mecanismos reguladores inmunológicos, eliminando o inhibiendo el crecimiento de ciertas células tumorales.

OBS

Sustancia producida por los macrófagos que tiene la capacidad de destruir células cancerígenas.

Save record 1

Record 2 2020-09-30

English

Subject field(s)
  • Cytology
  • Immunology
DEF

A protein that is released by activated macrophages as an immune system defense and, when the defense is overwhelmed, is a cause of cachexia or toxic shock ...

OBS

In some specialized works, the term «tumour necrosis factor» makes reference to the tumour necrosis factor alpha.

OBS

TNF-a: "a" refers to the Greek letter alpha.

Key term(s)
  • tumor necrosis factor alpha

French

Domaine(s)
  • Cytologie
  • Immunologie
CONT

Les facteurs nécrosant les tumeurs font partie des cytokines. Il en existe deux : le TNF alpha (également appelé cachectine, pour son rôle dans la cachexie liée aux maladies inflammatoires chroniques), produit par de nombreux types de cellules immunitaires (monocytes, lymphocytes), et le TNF bêta […]

OBS

Dans certains ouvrages spécialisés, le terme «facteur de nécrose tumorale» fait référence au facteur de nécrose tumorale alpha.

OBS

TNF a : La lettre «a» représente la lettre grecque.

Spanish

Save record 2

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TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
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